ID   CCA24_ARATH             Reviewed;         461 AA.
AC   Q9C968;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Cyclin-A2-4;
DE   AltName: Full=G2/mitotic-specific cyclin-A2-4;
DE            Short=CycA2;4;
GN   Name=CYCA2-4; OrderedLocusNames=At1g80370; ORFNames=F5I6.12;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=15208425; DOI=10.1104/pp.104.040436;
RA   Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA   Ma H.;
RT   "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT   phylogenetic analysis of plant cyclin-like proteins.";
RL   Plant Physiol. 135:1084-1099(2004).
CC   -!- INTERACTION:
CC       Q9C968; Q5CCK4: VAL2; NbExp=3; IntAct=EBI-25518099, EBI-15193683;
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AC018848; AAG52439.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE36392.1; -; Genomic_DNA.
DR   PIR; D96835; D96835.
DR   RefSeq; NP_178153.1; NM_106686.3.
DR   AlphaFoldDB; Q9C968; -.
DR   SMR; Q9C968; -.
DR   BioGRID; 29595; 10.
DR   IntAct; Q9C968; 1.
DR   STRING; 3702.AT1G80370.1; -.
DR   PaxDb; Q9C968; -.
DR   PRIDE; Q9C968; -.
DR   ProteomicsDB; 239155; -.
DR   EnsemblPlants; AT1G80370.1; AT1G80370.1; AT1G80370.
DR   GeneID; 844377; -.
DR   Gramene; AT1G80370.1; AT1G80370.1; AT1G80370.
DR   KEGG; ath:AT1G80370; -.
DR   Araport; AT1G80370; -.
DR   TAIR; locus:2034250; AT1G80370.
DR   eggNOG; KOG0654; Eukaryota.
DR   HOGENOM; CLU_020695_13_3_1; -.
DR   InParanoid; Q9C968; -.
DR   OMA; HGNCMER; -.
DR   OrthoDB; 993640at2759; -.
DR   PhylomeDB; Q9C968; -.
DR   PRO; PR:Q9C968; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9C968; baseline and differential.
DR   Genevisible; Q9C968; AT.
DR   GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IDA:TAIR.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0051301; P:cell division; IGI:TAIR.
DR   GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IGI:TAIR.
DR   GO; GO:0010374; P:stomatal complex development; IGI:TAIR.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Reference proteome.
FT   CHAIN           1..461
FT                   /note="Cyclin-A2-4"
FT                   /id="PRO_0000286996"
SQ   SEQUENCE   461 AA;  51637 MW;  7282354BBF7BA241 CRC64;
     MGKENAVSGN SIPIHGRPVT RALASALRAS SKLITSSEVA ATTQNQGRVL RAKSKRTALD
     EKKANAPKKR AVLKDITNVT CENSYTSCFS VAVENIKQIK KGRQSSSSSK VASSSATSQV
     TDAKVEVVSN SAGASLSVFT DTSLGTNETS YSIIAKPSSR SPPRPFGTVE RSCGGASSPK
     FVDIDSDDKD PLLCSLYAPD IYYNLRVAEL KRRPFPDFME KTQRDVTETM RGILVDWLVE
     VSEEYTLVPD TLYLTVYLID WFLHGNYVER QRLQLLGITC MLIASKYEEI HAPRIEEFCF
     ITDNTYTRDQ VLEMESQVLK HFSFQIYTPT SKTFLRRFLR AAQVSFPNQS LEMEFLANYL
     TELTLMDYPF LKFLPSIIAA SAVFLAKWTL NQSSHPWNPT LEHYTTYKAS DLKASVHALQ
     DLQLNTKGCS LNSIRMKYRQ DKFKSVAVFS SGELPDKLFI S