ZN767_HUMAN
ID ZN767_HUMAN Reviewed; 155 AA.
AC Q75MW2; D3DWG6; Q86WY4; Q9H9J3;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Protein ZNF767;
DE AltName: Full=Zinc finger protein 767 pseudogene;
GN Name=ZNF767P; Synonyms=ZNF767;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12853948; DOI=10.1038/nature01782;
RA Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA Wilson R.K.;
RT "The DNA sequence of human chromosome 7.";
RL Nature 424:157-164(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q75MW2-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q75MW2-2; Sequence=VSP_023681;
CC -!- CAUTION: Could be the product of a pseudogene. Despite its name, it
CC does not contain a canonical C2H2-type zinc-finger and in contrast to
CC other members of the krueppel C2H2-type zinc-finger protein family, it
CC is much shorter and lacks the C-terminus part. {ECO:0000305}.
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DR EMBL; AK022762; BAB14233.1; -; mRNA.
DR EMBL; AC004932; AAQ96876.1; -; Genomic_DNA.
DR EMBL; CH471146; EAW80038.1; -; Genomic_DNA.
DR EMBL; CH471146; EAW80039.1; -; Genomic_DNA.
DR EMBL; BC047675; AAH47675.1; -; mRNA.
DR AlphaFoldDB; Q75MW2; -.
DR SMR; Q75MW2; -.
DR IntAct; Q75MW2; 1.
DR iPTMnet; Q75MW2; -.
DR PhosphoSitePlus; Q75MW2; -.
DR BioMuta; HGNC:21884; -.
DR DMDM; 74712880; -.
DR EPD; Q75MW2; -.
DR MassIVE; Q75MW2; -.
DR PeptideAtlas; Q75MW2; -.
DR PRIDE; Q75MW2; -.
DR ProteomicsDB; 68639; -. [Q75MW2-1]
DR ProteomicsDB; 68640; -. [Q75MW2-2]
DR GeneCards; ZNF767P; -.
DR HGNC; HGNC:21884; ZNF767P.
DR neXtProt; NX_Q75MW2; -.
DR InParanoid; Q75MW2; -.
DR PhylomeDB; Q75MW2; -.
DR PathwayCommons; Q75MW2; -.
DR Reactome; R-HSA-212436; Generic Transcription Pathway.
DR ChiTaRS; ZNF767P; human.
DR Pharos; Q75MW2; Tdark.
DR PRO; PR:Q75MW2; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q75MW2; protein.
DR InterPro; IPR022137; Znf_prot_DUF3669.
DR Pfam; PF12417; DUF3669; 1.
PE 5: Uncertain;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..155
FT /note="Protein ZNF767"
FT /id="PRO_0000280456"
FT REGION 98..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 16..92
FT /evidence="ECO:0000255"
FT COMPBIAS 105..124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 109..155
FT /note="TTPSPSPRSSPRLNKGRSPATGAALTPRFQMFLWTPVQMQKLRPSRD -> V
FT PMTFDDVAV (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_023681"
FT VARIANT 31
FT /note="H -> R (in dbSNP:rs1723718)"
FT /id="VAR_057034"
FT VARIANT 38
FT /note="Q -> R (in dbSNP:rs1723719)"
FT /id="VAR_057035"
FT VARIANT 131
FT /note="A -> T (in dbSNP:rs1808231)"
FT /id="VAR_057036"
FT VARIANT 134
FT /note="T -> A (in dbSNP:rs354055)"
FT /id="VAR_057037"
FT CONFLICT 5
FT /note="A -> V (in Ref. 4; AAH47675)"
FT /evidence="ECO:0000305"
FT CONFLICT 89
FT /note="H -> R (in Ref. 4; AAH47675)"
FT /evidence="ECO:0000305"
FT CONFLICT 93
FT /note="F -> L (in Ref. 1; BAB14233)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 155 AA; 17236 MW; 217B194F114B23CD CRC64;
MEEAAAAPIS PWTMAATIQA MERKIESQAA HLLSLEGQTG MAEKKLADCE KTAVEFGNQL
EGKWAVLGTL LQEYGLLQRR LENVENLLHN RNFWILRLPP GSKGESPKTT PSPSPRSSPR
LNKGRSPATG AALTPRFQMF LWTPVQMQKL RPSRD
