ZN788_HUMAN
ID ZN788_HUMAN Reviewed; 82 AA.
AC Q6ZQV5; A0A0A0MSK0; M0R3I2; Q6ZRE4;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 28-MAR-2018, sequence version 3.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Putative KRAB domain-containing protein ZNF788 {ECO:0000305};
DE AltName: Full=Zinc finger family member 788, pseudogene {ECO:0000312|HGNC:HGNC:33112};
GN Name=ZNF788P {ECO:0000312|HGNC:HGNC:33112};
GN Synonyms=ZNF788 {ECO:0000312|HGNC:HGNC:33112};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Thymus, and Uterus;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q6ZQV5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q6ZQV5-2; Sequence=VSP_059376;
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC87366.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
CC Sequence=BAC87578.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
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DR EMBL; AK128282; BAC87366.1; ALT_SEQ; mRNA.
DR EMBL; AK128700; BAC87578.1; ALT_SEQ; mRNA.
DR EMBL; AC022415; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001335092.1; NM_001348163.1.
DR RefSeq; NP_001335093.1; NM_001348164.1.
DR RefSeq; NP_001335094.1; NM_001348165.1.
DR AlphaFoldDB; Q6ZQV5; -.
DR SMR; Q6ZQV5; -.
DR IntAct; Q6ZQV5; 1.
DR PhosphoSitePlus; Q6ZQV5; -.
DR BioMuta; ZNF788; -.
DR DMDM; 152112418; -.
DR MassIVE; Q6ZQV5; -.
DR MaxQB; Q6ZQV5; -.
DR PaxDb; Q6ZQV5; -.
DR PeptideAtlas; Q6ZQV5; -.
DR PRIDE; Q6ZQV5; -.
DR ProteomicsDB; 68092; -.
DR DNASU; 388507; -.
DR GeneID; 388507; -.
DR CTD; 388507; -.
DR GeneCards; ZNF788P; -.
DR HGNC; HGNC:33112; ZNF788P.
DR neXtProt; NX_Q6ZQV5; -.
DR InParanoid; Q6ZQV5; -.
DR OrthoDB; 1318335at2759; -.
DR PhylomeDB; Q6ZQV5; -.
DR PathwayCommons; Q6ZQV5; -.
DR SignaLink; Q6ZQV5; -.
DR BioGRID-ORCS; 388507; 0 hits in 79 CRISPR screens.
DR ChiTaRS; ZNF788; human.
DR GenomeRNAi; 388507; -.
DR Pharos; Q6ZQV5; Tdark.
DR PRO; PR:Q6ZQV5; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q6ZQV5; protein.
DR GO; GO:0005634; C:nucleus; HDA:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR Pfam; PF01352; KRAB; 1.
DR SMART; SM00349; KRAB; 1.
DR SUPFAM; SSF109640; SSF109640; 1.
DR PROSITE; PS50805; KRAB; 1.
PE 5: Uncertain;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..82
FT /note="Putative KRAB domain-containing protein ZNF788"
FT /id="PRO_0000293696"
FT DOMAIN 24..82
FT /note="KRAB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00119"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..21
FT /note="MRNMIPQDNENPPQQGEANQN -> M (in isoform 2)"
FT /id="VSP_059376"
SQ SEQUENCE 82 AA; 9552 MW; 3C8EAAB893A1EED5 CRC64;
MRNMIPQDNE NPPQQGEANQ NDSVAFEDVA VNFTPDEWAL LDPSQKNLYR EVMQETLRNL
ASIEVLWKRD SLKVKVISME KF
