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ZN830_XENTR
ID   ZN830_XENTR             Reviewed;         357 AA.
AC   Q6DJ13; Q28F24;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Zinc finger protein 830 {ECO:0000250|UniProtKB:Q96NB3};
DE   AltName: Full=Coiled-coil domain-containing protein 16 {ECO:0000250|UniProtKB:Q96NB3};
GN   Name=znf830 {ECO:0000250|UniProtKB:Q96NB3};
GN   Synonyms=ccdc16 {ECO:0000250|UniProtKB:Q96NB3}; ORFNames=TGas069h14.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as an important regulator of the cell cycle that
CC       participates in the maintenance of genome integrity.
CC       {ECO:0000250|UniProtKB:Q8R1N0}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8R1N0}.
CC       Chromosome {ECO:0000250|UniProtKB:Q8R1N0}. Nucleus speckle
CC       {ECO:0000250|UniProtKB:Q8R1N0}. Note=Excluded from nucleolus.
CC       {ECO:0000250|UniProtKB:Q8R1N0}.
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DR   EMBL; CR762210; CAJ81601.1; -; mRNA.
DR   EMBL; BC075372; AAH75372.1; -; mRNA.
DR   RefSeq; NP_001004918.1; NM_001004918.2.
DR   AlphaFoldDB; Q6DJ13; -.
DR   PaxDb; Q6DJ13; -.
DR   DNASU; 448299; -.
DR   Ensembl; ENSXETT00000023022; ENSXETP00000023022; ENSXETG00000010494.
DR   GeneID; 448299; -.
DR   KEGG; xtr:448299; -.
DR   CTD; 91603; -.
DR   Xenbase; XB-GENE-5806791; znf830.
DR   eggNOG; KOG3032; Eukaryota.
DR   HOGENOM; CLU_058140_1_0_1; -.
DR   InParanoid; Q6DJ13; -.
DR   OMA; EQIECYK; -.
DR   OrthoDB; 1458826at2759; -.
DR   PhylomeDB; Q6DJ13; -.
DR   TreeFam; TF315895; -.
DR   Reactome; R-XTR-6781823; Formation of TC-NER Pre-Incision Complex.
DR   Reactome; R-XTR-6782135; Dual incision in TC-NER.
DR   Reactome; R-XTR-6782210; Gap-filling DNA repair synthesis and ligation in TC-NER.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000010494; Expressed in ovary and 15 other tissues.
DR   ExpressionAtlas; Q6DJ13; baseline.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0044773; P:mitotic DNA damage checkpoint signaling; IBA:GO_Central.
DR   GO; GO:0033314; P:mitotic DNA replication checkpoint signaling; IBA:GO_Central.
DR   GO; GO:0033260; P:nuclear DNA replication; IBA:GO_Central.
DR   GO; GO:0048478; P:replication fork protection; IBA:GO_Central.
DR   InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR   InterPro; IPR040050; ZNF830-like.
DR   InterPro; IPR022755; Znf_C2H2_jaz.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   PANTHER; PTHR13278; PTHR13278; 1.
DR   Pfam; PF12171; zf-C2H2_jaz; 1.
DR   SMART; SM00451; ZnF_U1; 1.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Chromosome; Coiled coil; Developmental protein;
KW   Metal-binding; Mitosis; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..357
FT                   /note="Zinc finger protein 830"
FT                   /id="PRO_0000076198"
FT   ZN_FING         47..69
FT                   /note="C2H2-type"
FT   REGION          98..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          157..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          231..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          279..325
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        98..117
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   357 AA;  40577 MW;  84A0E8FAD216B60D CRC64;
     MADAGKKKLV QQEELRRLMK AKQRRSCSKK RIESPLAKYN SLGHLLCVVC NIQIKSELLW
     PAHILGKQHK EKVAELKGSK ANISSPSNKV QLHHIMKRKG SEPENQESKR IKGTEDQPTA
     LKTKLPEGFF ETEETSSAKH AAEKAPSLKL LAGDYEDDDE VEGEEYENVN EASTSLQKPA
     EIPLPPPTSS ADRLPADFFE SKMPLVSHSG SVLKADIQEK IVERKDNTAE ALPEGFFDDP
     EADAKVRKVD APKDQMDKEW EEFQKEIRQV NSVSDAIVAE EDEEGRLDRQ IDEIDEQIEC
     YRRVEHLRDL KDTLQDAKME VLKSKSSKKW QEEIGSDDEE TLPSLLYKNW RDKGAFL
 
 
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