ZN830_XENTR
ID ZN830_XENTR Reviewed; 357 AA.
AC Q6DJ13; Q28F24;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Zinc finger protein 830 {ECO:0000250|UniProtKB:Q96NB3};
DE AltName: Full=Coiled-coil domain-containing protein 16 {ECO:0000250|UniProtKB:Q96NB3};
GN Name=znf830 {ECO:0000250|UniProtKB:Q96NB3};
GN Synonyms=ccdc16 {ECO:0000250|UniProtKB:Q96NB3}; ORFNames=TGas069h14.1;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Gastrula;
RG Sanger Xenopus tropicalis EST/cDNA project;
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May act as an important regulator of the cell cycle that
CC participates in the maintenance of genome integrity.
CC {ECO:0000250|UniProtKB:Q8R1N0}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8R1N0}.
CC Chromosome {ECO:0000250|UniProtKB:Q8R1N0}. Nucleus speckle
CC {ECO:0000250|UniProtKB:Q8R1N0}. Note=Excluded from nucleolus.
CC {ECO:0000250|UniProtKB:Q8R1N0}.
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DR EMBL; CR762210; CAJ81601.1; -; mRNA.
DR EMBL; BC075372; AAH75372.1; -; mRNA.
DR RefSeq; NP_001004918.1; NM_001004918.2.
DR AlphaFoldDB; Q6DJ13; -.
DR PaxDb; Q6DJ13; -.
DR DNASU; 448299; -.
DR Ensembl; ENSXETT00000023022; ENSXETP00000023022; ENSXETG00000010494.
DR GeneID; 448299; -.
DR KEGG; xtr:448299; -.
DR CTD; 91603; -.
DR Xenbase; XB-GENE-5806791; znf830.
DR eggNOG; KOG3032; Eukaryota.
DR HOGENOM; CLU_058140_1_0_1; -.
DR InParanoid; Q6DJ13; -.
DR OMA; EQIECYK; -.
DR OrthoDB; 1458826at2759; -.
DR PhylomeDB; Q6DJ13; -.
DR TreeFam; TF315895; -.
DR Reactome; R-XTR-6781823; Formation of TC-NER Pre-Incision Complex.
DR Reactome; R-XTR-6782135; Dual incision in TC-NER.
DR Reactome; R-XTR-6782210; Gap-filling DNA repair synthesis and ligation in TC-NER.
DR Proteomes; UP000008143; Chromosome 6.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000010494; Expressed in ovary and 15 other tissues.
DR ExpressionAtlas; Q6DJ13; baseline.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0044773; P:mitotic DNA damage checkpoint signaling; IBA:GO_Central.
DR GO; GO:0033314; P:mitotic DNA replication checkpoint signaling; IBA:GO_Central.
DR GO; GO:0033260; P:nuclear DNA replication; IBA:GO_Central.
DR GO; GO:0048478; P:replication fork protection; IBA:GO_Central.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR040050; ZNF830-like.
DR InterPro; IPR022755; Znf_C2H2_jaz.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR PANTHER; PTHR13278; PTHR13278; 1.
DR Pfam; PF12171; zf-C2H2_jaz; 1.
DR SMART; SM00451; ZnF_U1; 1.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Chromosome; Coiled coil; Developmental protein;
KW Metal-binding; Mitosis; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..357
FT /note="Zinc finger protein 830"
FT /id="PRO_0000076198"
FT ZN_FING 47..69
FT /note="C2H2-type"
FT REGION 98..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 279..325
FT /evidence="ECO:0000255"
FT COMPBIAS 98..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 40577 MW; 84A0E8FAD216B60D CRC64;
MADAGKKKLV QQEELRRLMK AKQRRSCSKK RIESPLAKYN SLGHLLCVVC NIQIKSELLW
PAHILGKQHK EKVAELKGSK ANISSPSNKV QLHHIMKRKG SEPENQESKR IKGTEDQPTA
LKTKLPEGFF ETEETSSAKH AAEKAPSLKL LAGDYEDDDE VEGEEYENVN EASTSLQKPA
EIPLPPPTSS ADRLPADFFE SKMPLVSHSG SVLKADIQEK IVERKDNTAE ALPEGFFDDP
EADAKVRKVD APKDQMDKEW EEFQKEIRQV NSVSDAIVAE EDEEGRLDRQ IDEIDEQIEC
YRRVEHLRDL KDTLQDAKME VLKSKSSKKW QEEIGSDDEE TLPSLLYKNW RDKGAFL