ZN865_XENTR
ID ZN865_XENTR Reviewed; 942 AA.
AC B1H2Q6;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 1.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=Zinc finger protein 865;
GN Name=znf865;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in transcriptional regulation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC161090; AAI61090.1; -; mRNA.
DR RefSeq; NP_001120386.1; NM_001126914.1.
DR AlphaFoldDB; B1H2Q6; -.
DR SMR; B1H2Q6; -.
DR STRING; 8364.ENSXETP00000041502; -.
DR PaxDb; B1H2Q6; -.
DR GeneID; 100145461; -.
DR KEGG; xtr:100145461; -.
DR CTD; 100507290; -.
DR Xenbase; XB-GENE-5959428; znf865.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_010472_0_0_1; -.
DR InParanoid; B1H2Q6; -.
DR OMA; PTPQWGI; -.
DR OrthoDB; 1318335at2759; -.
DR PhylomeDB; B1H2Q6; -.
DR TreeFam; TF350857; -.
DR Proteomes; UP000008143; Chromosome 7.
DR Proteomes; UP000790000; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF00096; zf-C2H2; 12.
DR SMART; SM00355; ZnF_C2H2; 20.
DR SUPFAM; SSF57667; SSF57667; 11.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 20.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 20.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..942
FT /note="Zinc finger protein 865"
FT /id="PRO_0000404596"
FT ZN_FING 172..194
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 200..222
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 282..304
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 310..332
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 338..360
FT /note="C2H2-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 367..389
FT /note="C2H2-type 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 466..488
FT /note="C2H2-type 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 494..516
FT /note="C2H2-type 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 522..544
FT /note="C2H2-type 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 564..586
FT /note="C2H2-type 10"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 592..614
FT /note="C2H2-type 11"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 678..700
FT /note="C2H2-type 12"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 706..728
FT /note="C2H2-type 13"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 734..756
FT /note="C2H2-type 14"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 762..784
FT /note="C2H2-type 15"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 790..812
FT /note="C2H2-type 16"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 818..840
FT /note="C2H2-type 17"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 846..868
FT /note="C2H2-type 18"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 874..896
FT /note="C2H2-type 19"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 902..924
FT /note="C2H2-type 20"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT REGION 66..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 942 AA; 106352 MW; 498C86D441F7DB0D CRC64;
MEANAGDEGI HFQNYPFDFL EFLNHQRFEP MELYNHHEHA KAVAALPCAP PQYEYNHQTQ
PNHVQFASTS TSKPKEFKVE APPSSSLSPS KKPDIATTQQ FNNQPPITTT QTIFDSTFNA
AQWGIVDLSS HQHLFNNLKR SLPVAQQLPA EDENKDDKNY FRRLKYLIDR RFPCTVCQKS
FKQSSHLVQH MLVHTGERPY ECNTCGRTYN HISSLIRHRR CHKEETEAEV TNSVPPPDGE
AAAAAAVVAA AAAAMSEAAA GSAEMPVTGS EQSIPLPQDG PFTCTLCWKV FKKQSHLHQH
QIIHTGEKPF SCSVCAKSFN RRESLKRHVK THSDSMKVQC EVCGKSFRDT SYLLKHQATH
TGERPDYKCE LCGKSYAAPQ SLLRHKQVHE QGLALQQPMV QQQQPLSEVI KEPTSSVTIE
AASLLGTDVS NVGPAAISVI GKIGSFFSQS SLQKPPSVIN NANKNFCCNV CGRGFGRRET
LKRHERIHTG EKPHQCSVCG KRFRESFHLT KHHVVHTRER PYKCELCGKV FGYPQSLTRH
KQIHRLQLPC TVATGTLPPD RLTFGCTDCG ERFPDSFHLM NHKELHMNEK PYVCDTCGKC
FGFIENLMWH KLVHQTAAER LHPISQCQDV AESQQVNCLE TTAPSDVSGA EVAAAAAAAG
VVASPFEEHP VVPSGERFSC SICGQSFKHF LGLVTHKYVH LVRRTLACNV CGQNFAGAYD
LLLHRRTHLQ KRHFTCSVCG KRFWEAALLM RHQRCHTEER PYRCTICGRG FLHSWYLRQH
KVVHTGERAY KCALCNKRFA QSSSLAEHQR LHIVARPQRC PTCGKTFRYR SNLLEHQRVH
LGEKVYRCDQ CGKSFFYISS ILRHQRSHDA KPDLRCSCCL KLFKDPKYFS KHVQTHQGGR
PFKCGACGEA FSNTYGLKKH RHAHKMERLA AAAALVEGQK TL
