ID   ZNF19_PONAB             Reviewed;         446 AA.
AC   Q5R7I8;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Zinc finger protein 19;
GN   Name=ZNF19;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in transcriptional regulation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR860128; CAH92272.1; -; mRNA.
DR   RefSeq; NP_001126327.1; NM_001132855.2.
DR   AlphaFoldDB; Q5R7I8; -.
DR   SMR; Q5R7I8; -.
DR   STRING; 9601.ENSPPYP00000008503; -.
DR   GeneID; 100173308; -.
DR   KEGG; pon:100173308; -.
DR   CTD; 7567; -.
DR   eggNOG; KOG1721; Eukaryota.
DR   InParanoid; Q5R7I8; -.
DR   OrthoDB; 1318335at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd07765; KRAB_A-box; 1.
DR   InterPro; IPR001909; KRAB.
DR   InterPro; IPR036051; KRAB_dom_sf.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF01352; KRAB; 1.
DR   Pfam; PF00096; zf-C2H2; 9.
DR   SMART; SM00349; KRAB; 1.
DR   SMART; SM00355; ZnF_C2H2; 9.
DR   SUPFAM; SSF109640; SSF109640; 1.
DR   SUPFAM; SSF57667; SSF57667; 6.
DR   PROSITE; PS50805; KRAB; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 9.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..446
FT                   /note="Zinc finger protein 19"
FT                   /id="PRO_0000367590"
FT   DOMAIN          2..73
FT                   /note="KRAB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00119"
FT   ZN_FING         149..171
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         177..199
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         205..227
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         233..255
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         261..283
FT                   /note="C2H2-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         289..311
FT                   /note="C2H2-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         317..339
FT                   /note="C2H2-type 7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         345..367
FT                   /note="C2H2-type 8"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         373..395
FT                   /note="C2H2-type 9"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         401..423
FT                   /note="C2H2-type 10; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ   SEQUENCE   446 AA;  51000 MW;  760AF106AE7955D2 CRC64;
     MVTFEDVAVH FTKTEWTGLS PAQRALYRSV MLENFGNLTA LGYPVPKPAL ISLLEGGDMA
     WGLEAQDDPP AETTKNVRKD VETNIDSEST LIQGISEERD GMMSHGQLKS VPQRTDFPET
     CNVEKHQDIP TVKNIRGKVP RIPCARKPFI CEECGKSFSY FSYYARHQRI HTGEKPFECS
     ECGKAFNGNS SLIRHQRIHT GEKPYQCEEC GRAFNDNANL IRHQRIHSGD RPYYCTECGN
     SFTSSSEFVI HQRIHTGEKP YECNECGKAF VGNSPLLRHQ KIHTGEKPYE CNECGKSFGR
     TSHLSQHQRI HTGEKPYSCK VCGQAFNFHT KLTRHQRIHS EEKPFDCVDC GKAFSAQEQL
     KRHLRIHTQE SSYVCDECGK AFTSKRNLHQ HQRIHTGEKP YEYSKYEKAF GTSSQLGHLE
     HVHSGEKPVL DICRFGLPEF FTPFYW