ID   ZNF27_ASPFN             Reviewed;          91 AA.
AC   B8MYS5;
DT   11-MAY-2016, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Transcription factor znf27 {ECO:0000305};
DE   AltName: Full=Asparasone A synthesis protein znf27 {ECO:0000305};
GN   Name=znf27 {ECO:0000303|PubMed:24412484}; ORFNames=AFLA_082140;
OS   Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS   / JCM 12722 / SRRC 167).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=332952;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC
RC   167;
RX   PubMed=25883274; DOI=10.1128/genomea.00168-15;
RA   Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA   Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT   "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT   aflatoxin contamination of food and feed.";
RL   Genome Announc. 3:E0016815-E0016815(2015).
RN   [2]
RP   INDUCTION, DISRUPTION PHENOTYPE, AND FUNCTION.
RX   PubMed=24412484; DOI=10.1016/j.fgb.2014.01.001;
RA   Cary J.W., Harris-Coward P.Y., Ehrlich K.C., Di Mavungu J.D.,
RA   Malysheva S.V., De Saeger S., Dowd P.F., Shantappa S., Martens S.L.,
RA   Calvo A.M.;
RT   "Functional characterization of a veA-dependent polyketide synthase gene in
RT   Aspergillus flavus necessary for the synthesis of asparasone, a sclerotium-
RT   specific pigment.";
RL   Fungal Genet. Biol. 64:25-35(2014).
CC   -!- FUNCTION: Transcription factor; part of the gene cluster 27 that
CC       mediates the biosynthesis of asparasone A, a sclerotium-specific
CC       anthraquinone pigment important for sclerotial survival
CC       (PubMed:24412484). Controls the expression of the non-reducing
CC       polyketide synthase (NRPKS) pks27 (PubMed:24412484).
CC       {ECO:0000269|PubMed:24412484}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- INDUCTION: Expression is induced by the developmental and secondary
CC       metabolism regulator veA (PubMed:24412484).
CC       {ECO:0000269|PubMed:24412484}.
CC   -!- DISRUPTION PHENOTYPE: Impairs the production of asparasone A
CC       (PubMed:24412484). {ECO:0000269|PubMed:24412484}.
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DR   EMBL; EQ963472; EED57517.1; -; Genomic_DNA.
DR   RefSeq; XP_002373129.1; XM_002373088.1.
DR   AlphaFoldDB; B8MYS5; -.
DR   EnsemblFungi; EED57517; EED57517; AFLA_082140.
DR   VEuPathDB; FungiDB:AFLA_082140; -.
DR   HOGENOM; CLU_2426603_0_0_1; -.
DR   Proteomes; UP000001875; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..91
FT                   /note="Transcription factor znf27"
FT                   /id="PRO_0000436133"
SQ   SEQUENCE   91 AA;  10080 MW;  210FE3ADB6025E8A CRC64;
     MTSQWKCPAK DQSLRNIQRN RRRLGDSGLP ATVVRCSKSG ATRRNPAVND ASQCSSIVST
     VRIGGKDGRH QPKLQSRVLI FELEDKSLST E