ID   CCAP_CARMA              Reviewed;           9 AA.
AC   P84119; P38556;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   31-AUG-2004, sequence version 1.
DT   11-DEC-2019, entry version 30.
DE   RecName: Full=Cardioactive peptide;
DE   AltName: Full=Crustacean cardioactive peptide;
DE            Short=CCAP;
OS   Carcinus maenas (Common shore crab) (Green crab).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Brachyura;
OC   Eubrachyura; Portunoidea; Carcinidae; Carcinus.
OX   NCBI_TaxID=6759;
RN   [1]
RP   PROTEIN SEQUENCE, AMIDATION AT CYS-9, SUBCELLULAR LOCATION, AND TISSUE
RP   SPECIFICITY.
RC   TISSUE=Pericardial organs;
RX   PubMed=16593803; DOI=10.1073/pnas.84.2.575;
RA   Stangier J., Hilbich C., Beyreuther K., Keller R.;
RT   "Unusual cardioactive peptide (CCAP) from pericardial organs of the shore
RT   crab Carcinus maenas.";
RL   Proc. Natl. Acad. Sci. U.S.A. 84:575-579(1987).
CC   -!- FUNCTION: Cardioregulatory neurohormone that increases heart beat rate
CC       during adult wing inflation; has no effect on beat amplitude. The
CC       effect of CCAP is both ino- and chronotropic.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16593803}.
CC   -!- TISSUE SPECIFICITY: Stored in pericardial organs and released into the
CC       hemolymph. {ECO:0000269|PubMed:16593803}.
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DR   PIR; A26363; A26363.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Disulfide bond; Hormone;
KW   Neuropeptide; Secreted.
FT   PEPTIDE         1..9
FT                   /note="Cardioactive peptide"
FT                   /id="PRO_0000044115"
FT   MOD_RES         9
FT                   /note="Cysteine amide"
FT                   /evidence="ECO:0000269|PubMed:16593803"
FT   DISULFID        3..9
SQ   SEQUENCE   9 AA;  959 MW;  C5A861A9CDD44EB9 CRC64;
     PFCNAFTGC