ID   CCAP_SPOER              Reviewed;           9 AA.
AC   P84121; P38556;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   31-AUG-2004, sequence version 1.
DT   02-JUN-2021, entry version 30.
DE   RecName: Full=Cardioactive peptide;
DE   AltName: Full=Crustacean cardioactive peptide;
DE            Short=CCAP;
OS   Spodoptera eridania (Southern armyworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Amphipyrinae; Spodoptera.
OX   NCBI_TaxID=37547;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT CYS-9.
RC   TISSUE=Head;
RX   PubMed=8129851; DOI=10.1515/bchm3.1993.374.7-12.1065;
RA   Furuya K., Liao S., Reynolds S.E., Ota R.B., Hackett M., Schooley D.A.;
RT   "Isolation and identification of a cardioactive peptide from Tenebrio
RT   molitor and Spodoptera eridania.";
RL   Biol. Chem. Hoppe-Seyler 374:1065-1074(1993).
CC   -!- FUNCTION: Cardioregulatory neurohormone that increases heart beat rate
CC       during adult wing inflation; has no effect on beat amplitude. The
CC       effect of CCAP is both ino- and chronotropic.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Disulfide bond; Hormone;
KW   Neuropeptide; Secreted.
FT   PEPTIDE         1..9
FT                   /note="Cardioactive peptide"
FT                   /id="PRO_0000044116"
FT   MOD_RES         9
FT                   /note="Cysteine amide"
FT                   /evidence="ECO:0000269|PubMed:8129851"
FT   DISULFID        3..9
SQ   SEQUENCE   9 AA;  959 MW;  C5A861A9CDD44EB9 CRC64;
     PFCNAFTGC