ID   ZNTB_PECAS              Reviewed;         327 AA.
AC   Q6D5P8;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Zinc transport protein ZntB {ECO:0000255|HAMAP-Rule:MF_01565};
GN   Name=zntB {ECO:0000255|HAMAP-Rule:MF_01565}; OrderedLocusNames=ECA1993;
OS   Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS   carotovora subsp. atroseptica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=218491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCRI 1043 / ATCC BAA-672;
RX   PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA   Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA   Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA   Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA   Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA   Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA   Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT   "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT   subsp. atroseptica and characterization of virulence factors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC   -!- FUNCTION: Zinc transporter. Acts as a Zn(2+):proton symporter, which
CC       likely mediates zinc ion uptake. {ECO:0000255|HAMAP-Rule:MF_01565}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+)(out) + Zn(2+)(out) = H(+)(in) + Zn(2+)(in);
CC         Xref=Rhea:RHEA:71195, ChEBI:CHEBI:15378, ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01565};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:71196;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01565};
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01565}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01565}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01565}.
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DR   EMBL; BX950851; CAG74894.1; -; Genomic_DNA.
DR   RefSeq; WP_011093555.1; NC_004547.2.
DR   AlphaFoldDB; Q6D5P8; -.
DR   SMR; Q6D5P8; -.
DR   STRING; 218491.ECA1993; -.
DR   EnsemblBacteria; CAG74894; CAG74894; ECA1993.
DR   KEGG; eca:ECA1993; -.
DR   PATRIC; fig|218491.5.peg.2030; -.
DR   eggNOG; COG0598; Bacteria.
DR   HOGENOM; CLU_007127_2_0_6; -.
DR   OMA; MVSVRIF; -.
DR   OrthoDB; 822653at2; -.
DR   Proteomes; UP000007966; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:InterPro.
DR   HAMAP; MF_01565; ZntB; 1.
DR   InterPro; IPR045861; CorA_cytoplasmic_dom.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   InterPro; IPR023714; Zn_transp_ZntB.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF143865; SSF143865; 1.
DR   SUPFAM; SSF144083; SSF144083; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport; Zinc.
FT   CHAIN           1..327
FT                   /note="Zinc transport protein ZntB"
FT                   /id="PRO_0000239242"
FT   TOPO_DOM        1..271
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01565"
FT   TRANSMEM        272..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01565"
FT   TOPO_DOM        293..300
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01565"
FT   TRANSMEM        301..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01565"
FT   TOPO_DOM        322..327
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01565"
SQ   SEQUENCE   327 AA;  36505 MW;  D20A32A4067ACED3 CRC64;
     MESFAGKELQ HSGAVHAYQL DGKGGITPIG EQDVVNSEKP CWLHLDSTVP ASARWLNKTL
     VVPDSVRTAL AGESVRPRVT RLGEGTLITL RSINLNANAR PDQLVAVRVF ITDKLIISTR
     RRKILAIDEI LTDLKEGNGP TDSGNWLVSI AEALTDHTSE FIDDLHEKII DLEDDLLEQK
     IPPRGELALI RKQLIVLRRY MTPQRDVFSR ISGEKLPWMQ DDDRRRMQEI ADRLGRGLED
     LDASVARTTV LSDEITALMT EAMNRRTYTM SLLAMVFLPT TFLTGLFGVN LGGIPGGDAP
     FGFFTFCLML VILVGGVAWW LKRSKWL