ZNTB_SHIBS
ID ZNTB_SHIBS Reviewed; 327 AA.
AC Q320D7;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Zinc transport protein ZntB {ECO:0000255|HAMAP-Rule:MF_01565};
GN Name=zntB {ECO:0000255|HAMAP-Rule:MF_01565}; OrderedLocusNames=SBO_1719;
OS Shigella boydii serotype 4 (strain Sb227).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=300268;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sb227;
RX PubMed=16275786; DOI=10.1093/nar/gki954;
RA Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA Jin Q.;
RT "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT bacillary dysentery.";
RL Nucleic Acids Res. 33:6445-6458(2005).
CC -!- FUNCTION: Zinc transporter. Acts as a Zn(2+):proton symporter, which
CC likely mediates zinc ion uptake. {ECO:0000255|HAMAP-Rule:MF_01565}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+)(out) + Zn(2+)(out) = H(+)(in) + Zn(2+)(in);
CC Xref=Rhea:RHEA:71195, ChEBI:CHEBI:15378, ChEBI:CHEBI:29105;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01565};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:71196;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01565};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01565}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01565}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000255|HAMAP-Rule:MF_01565}.
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DR EMBL; CP000036; ABB66321.1; -; Genomic_DNA.
DR RefSeq; WP_000387388.1; NC_007613.1.
DR AlphaFoldDB; Q320D7; -.
DR SMR; Q320D7; -.
DR EnsemblBacteria; ABB66321; ABB66321; SBO_1719.
DR GeneID; 66674830; -.
DR KEGG; sbo:SBO_1719; -.
DR HOGENOM; CLU_007127_2_0_6; -.
DR OMA; MVSVRIF; -.
DR Proteomes; UP000007067; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:InterPro.
DR HAMAP; MF_01565; ZntB; 1.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR023714; Zn_transp_ZntB.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; SSF143865; 1.
DR SUPFAM; SSF144083; SSF144083; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Transmembrane;
KW Transmembrane helix; Transport; Zinc.
FT CHAIN 1..327
FT /note="Zinc transport protein ZntB"
FT /id="PRO_0000239248"
FT TOPO_DOM 1..273
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01565"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01565"
FT TOPO_DOM 295..300
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01565"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01565"
FT TOPO_DOM 322..327
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01565"
SQ SEQUENCE 327 AA; 36612 MW; B3A83F420565775D CRC64;
MEAIKGSDVN VPDAVFAWML DGRGGVKPLE NTDVIDEAHP CWLHLNYVHH DSAQWLATTP
LLPNNVRDAL AGESTRPRVS RLGEGTLITL RCINGSTDER PDQLVAMRVY MDGRLIVSTR
QRKVLALDDV VSDLEEGTGP TDCGGWLVDV CDALTDHSSE FIEQLHDKII DLEDNLLDQQ
IPPRGFLALL RKQLIVMRRY MAPQRDVYAR LASERLPWMS DDQRRRMQDI ADRLGRGLDE
IDACIARTGV MADEIAQVMQ ENLARRTYTM SLMAMVFLPS TFLTGLFGVN LGGIPGGGWQ
FGFSIFCILL VVLIGGVALW LHRSKWL
