ID   ZNUB_HAEIN              Reviewed;         261 AA.
AC   P44691;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=High-affinity zinc uptake system membrane protein ZnuB;
GN   Name=znuB; OrderedLocusNames=HI_0407;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Involved in the high-affinity zinc uptake transport system.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC-3 integral membrane protein family.
CC       {ECO:0000305}.
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DR   EMBL; L42023; AAC22066.1; -; Genomic_DNA.
DR   PIR; A64066; A64066.
DR   RefSeq; NP_438569.1; NC_000907.1.
DR   RefSeq; WP_005693761.1; NC_000907.1.
DR   AlphaFoldDB; P44691; -.
DR   SMR; P44691; -.
DR   STRING; 71421.HI_0407; -.
DR   EnsemblBacteria; AAC22066; AAC22066; HI_0407.
DR   KEGG; hin:HI_0407; -.
DR   PATRIC; fig|71421.8.peg.426; -.
DR   eggNOG; COG1108; Bacteria.
DR   HOGENOM; CLU_028808_3_2_6; -.
DR   OMA; RIDLMAY; -.
DR   PhylomeDB; P44691; -.
DR   BioCyc; HINF71421:G1GJ1-422-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0010043; P:response to zinc ion; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3470.10; -; 1.
DR   InterPro; IPR037294; ABC_BtuC-like.
DR   InterPro; IPR001626; ABC_TroCD.
DR   PANTHER; PTHR30477; PTHR30477; 1.
DR   Pfam; PF00950; ABC-3; 1.
DR   SUPFAM; SSF81345; SSF81345; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport; Zinc;
KW   Zinc transport.
FT   CHAIN           1..261
FT                   /note="High-affinity zinc uptake system membrane protein
FT                   ZnuB"
FT                   /id="PRO_0000171162"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   261 AA;  28466 MW;  DD2AC8F0DF6CBE96 CRC64;
     MFEILFPALL TGIVLSLITA PLGVFVVWRK MAYFGDTLSH SALLGVALGI FLQVNPYIAI
     VVLTLILAIA MVWLESNTQF SIDTLLGIIA HSCLSLGVVT VGLLRNVRVD LMNYLFGDLL
     AINYTDLIYI GIGVIIVLST LIYFWQSLLS TTVSPELAQV EGINIKKMRF ILMILTALTI
     ALSMKFVGAL IITSLLIIPA ATARRFARTP ESMVGWAIIM SMLSIIGGLI LSAFYDTAAG
     PSVVICSAFL FVLSLFKRER L