ZNUC1_HAHCH
ID ZNUC1_HAHCH Reviewed; 255 AA.
AC Q2SPI3;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Zinc import ATP-binding protein ZnuC 1 {ECO:0000255|HAMAP-Rule:MF_01725};
DE EC=7.2.2.20 {ECO:0000255|HAMAP-Rule:MF_01725};
GN Name=znuC1 {ECO:0000255|HAMAP-Rule:MF_01725}; OrderedLocusNames=HCH_00536;
OS Hahella chejuensis (strain KCTC 2396).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC Hahellaceae; Hahella.
OX NCBI_TaxID=349521;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 2396;
RX PubMed=16352867; DOI=10.1093/nar/gki1016;
RA Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G.,
RA Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K.,
RA Oh T.K., Kim J.F.;
RT "Genomic blueprint of Hahella chejuensis, a marine microbe producing an
RT algicidal agent.";
RL Nucleic Acids Res. 33:7066-7073(2005).
CC -!- FUNCTION: Part of the ABC transporter complex ZnuABC involved in zinc
CC import. Responsible for energy coupling to the transport system.
CC {ECO:0000255|HAMAP-Rule:MF_01725}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP(in) + H2O(in) + Zn(2+)(out) = ADP(in) + H(+)(in) +
CC phosphate(in) + Zn(2+)(in); Xref=Rhea:RHEA:29795, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:29105, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.2.2.20;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01725};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (ZnuC),
CC two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA).
CC {ECO:0000255|HAMAP-Rule:MF_01725}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01725}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01725}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Zinc importer
CC (TC 3.A.1.15.5) family. {ECO:0000255|HAMAP-Rule:MF_01725}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000155; ABC27441.1; -; Genomic_DNA.
DR RefSeq; WP_011394518.1; NC_007645.1.
DR AlphaFoldDB; Q2SPI3; -.
DR SMR; Q2SPI3; -.
DR STRING; 349521.HCH_00536; -.
DR EnsemblBacteria; ABC27441; ABC27441; HCH_00536.
DR KEGG; hch:HCH_00536; -.
DR eggNOG; COG1121; Bacteria.
DR HOGENOM; CLU_000604_1_11_6; -.
DR OMA; GHDHVHP; -.
DR OrthoDB; 1721927at2; -.
DR Proteomes; UP000000238; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015633; F:ABC-type zinc transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR017882; ZnuC.
DR PANTHER; PTHR42734:SF9; PTHR42734:SF9; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS51298; ZNUC; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW Nucleotide-binding; Reference proteome; Translocase; Transport; Zinc;
KW Zinc transport.
FT CHAIN 1..255
FT /note="Zinc import ATP-binding protein ZnuC 1"
FT /id="PRO_0000281511"
FT DOMAIN 7..220
FT /note="ABC transporter"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01725"
FT REGION 229..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 39..46
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01725"
SQ SEQUENCE 255 AA; 28178 MW; FCFB391F594C658F CRC64;
MNPPPLIRLQ DVTVKIQGRT LIENVTFDIN SGEIITVIGP NGAGKSTLAK ALLGIQPLSR
GEVLRRPGLK IGYMPQRFHI DASLPLTVKR FLQLAHNPQR WREALQRVEM EHVAKQPMHT
LSGGELQRVL LARALQRAPD LLVLDEPAQG VDVTGQAELY RLIRSLRDEL HCGALLVSHD
LHLVMASTDQ VLCLNRHICC AGHPEKVSNE PAFINLFGTQ AARSLAVYHH HHDHHHHTDG
TVAAGSECSH GDQHA