ID   ZO22_XENLA              Reviewed;         435 AA.
AC   P18745;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Oocyte zinc finger protein XlCOF22;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=3139407; DOI=10.1002/j.1460-2075.1988.tb03002.x;
RA   Koester M., Pieler T., Poeting A., Knoechel W.;
RT   "The finger motif defines a multigene family represented in the maternal
RT   mRNA of Xenopus laevis oocytes.";
RL   EMBO J. 7:1735-1741(1988).
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; S00833; S00833.
DR   AlphaFoldDB; P18745; -.
DR   SMR; P18745; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 10.
DR   SMART; SM00355; ZnF_C2H2; 12.
DR   SUPFAM; SSF57667; SSF57667; 7.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 12.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 12.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..435
FT                   /note="Oocyte zinc finger protein XlCOF22"
FT                   /id="PRO_0000047820"
FT   ZN_FING         97..120
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         126..148
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         154..176
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         182..204
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         210..232
FT                   /note="C2H2-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         238..260
FT                   /note="C2H2-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         266..288
FT                   /note="C2H2-type 7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         294..316
FT                   /note="C2H2-type 8"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         322..345
FT                   /note="C2H2-type 9"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         351..373
FT                   /note="C2H2-type 10"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         379..402
FT                   /note="C2H2-type 11"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         408..430
FT                   /note="C2H2-type 12"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          71..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   435 AA;  49417 MW;  FE83299ACFD4D8F3 CRC64;
     MGCSLNNNSQ DDYVSFVIKE EEASCEEGNQ SDCSINPLTE PIQGTDTPTP NMLYSLVRDF
     LKTNGNKYDE NANTSAHFSR NRDSDKHERT HTGKKLHSCS QCGKCFSSSS DLLAHRRQSH
     TREKPFSCSE CGKCFSFRSR LIDHQRTHTG EKPFCCFQCG KSFSVRSRFL DHRRTHTGEK
     PFSCLECGKC FLFRSRLLEH QRTHTGEKPF SCLKCGKCFS VRSRLKDHQR THTGEKPFSC
     LECGKSFSFR PCLIDHQRTH TGEKPFSCFQ CGKCFSFQSR LINHQRTHTG EKPFSCSECG
     KSFSNQSCLR VHQRTHTGEK PYSCSECGKS FVTSSQLAVH RRRTHTGEKP FSCSECGKCF
     SNQSCLRVHQ RTHTGENLFS CSECGKSFVT SSKLASHQRQ THTGEKPVSC SECGKCFTRK
     RSLKVHFKIH TGGKP