ID   ZO29_XENLA              Reviewed;         537 AA.
AC   P18748;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Oocyte zinc finger protein XlCOF29;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 1-397.
RX   PubMed=2503827; DOI=10.1073/pnas.86.16.6097;
RA   Knoechel W., Poeting A., Koester M., el Baradi T., Nietfeld W.,
RA   Bouwmeester T., Pieler T.;
RT   "Evolutionary conserved modules associated with zinc fingers in Xenopus
RT   laevis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:6097-6100(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 370-537.
RX   PubMed=2509712; DOI=10.1016/0022-2836(89)90155-1;
RA   Nietfeld W., El-Baradi T., Mentzel H., Pieler T., Koester M., Poeting A.,
RA   Knoechel W.;
RT   "Second-order repeats in Xenopus laevis finger proteins.";
RL   J. Mol. Biol. 208:639-659(1989).
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; M25870; AAA50017.1; -; mRNA.
DR   PIR; E33282; E33282.
DR   PIR; S06557; S06557.
DR   AlphaFoldDB; P18748; -.
DR   SMR; P18748; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 6.
DR   SMART; SM00355; ZnF_C2H2; 6.
DR   SUPFAM; SSF57667; SSF57667; 3.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 6.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..537
FT                   /note="Oocyte zinc finger protein XlCOF29"
FT                   /id="PRO_0000047823"
FT   ZN_FING         375..397
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         403..425
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         431..453
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         459..481
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         487..509
FT                   /note="C2H2-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         515..537
FT                   /note="C2H2-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   537 AA;  59983 MW;  634F1B4C89A3801F CRC64;
     MGMSEKASDT GMKGKKKDKN ERNEKILNLT LEMIYLLTGE GYVIPKKKKS GDDMAPPQSC
     TDCILEGGCR CHVTNLTGGR ALHAPGSVIQ KENNKNDKKI LELVSNIIQL LTGEEWEYIK
     RKKALYMEGI KEDPQQLSQW CEYEDKSIVM CNLEATACLN NDPRNDTVFC EHRDLSKFDT
     SLAEQSLPAI GIKGEPVSCE GANQSDCNIN PLAEQIQGTD TPTPIMGCSL NNSLSDNYIS
     NGIKTEATSC EAGNQSDYGN NPVAEVQLTD TTTPVKRCSL NSILSDNYIK IAIKEEPPSW
     EDENQTHCSI NAPGEQNEEI DTPTSIMRFC LNSSLLDSSL LNAIKDDTLS CEGENYSDCS
     FNPLTEQTSP GCKQFTCSEC GKTYTRLYNL KIHLKSHTDD KTFSCSECEE CFTDHTDLVI
     HRRLHLTLKA FPCAECGKCF TNCTNLRAHS KTHTGEKPYS CTECGKTFRD RSHLNIHKKR
     HTGEKPYTCS ECGKCFAYRS NLMVHVRIHT GEKPFSCSKC GKCFTDHANL IVHERMH