ZO2_XENLA
ID ZO2_XENLA Reviewed; 157 AA.
AC P18743;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1990, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Oocyte zinc finger protein XlCOF2;
DE Flags: Fragment;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=2509712; DOI=10.1016/0022-2836(89)90155-1;
RA Nietfeld W., El-Baradi T., Mentzel H., Pieler T., Koester M., Poeting A.,
RA Knoechel W.;
RT "Second-order repeats in Xenopus laevis finger proteins.";
RL J. Mol. Biol. 208:639-659(1989).
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR PIR; S05632; S05632.
DR AlphaFoldDB; P18743; -.
DR SMR; P18743; -.
DR Proteomes; UP000186698; Genome assembly.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF00096; zf-C2H2; 4.
DR SMART; SM00355; ZnF_C2H2; 5.
DR SUPFAM; SSF57667; SSF57667; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN <1..>157
FT /note="Oocyte zinc finger protein XlCOF2"
FT /id="PRO_0000047808"
FT ZN_FING 6..28
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 34..56
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 79..101
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 107..129
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 135..157
FT /note="C2H2-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT NON_TER 1
FT NON_TER 157
SQ SEQUENCE 157 AA; 17953 MW; 5386C35255E9AAA6 CRC64;
TGEKPFTCTE CGKNFSFTTS FIRHMRIHTG EKPYSCADCG KHFSEKMYLQ FHQKNPSECE
EYVTLKATLQ SHQSVEKPFT CTECGKCFSL SSYLHRHQRL HTGDRPFSCA ECGKAFSGKA
QLQDHQNTHT GEKPFTCTEC GKCFTRKGSL QMHQKIH