ID   ZO72_XENLA              Reviewed;         391 AA.
AC   P18752;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Oocyte zinc finger protein XlCOF7.2;
DE   Flags: Fragment;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 1-306.
RX   PubMed=2503827; DOI=10.1073/pnas.86.16.6097;
RA   Knoechel W., Poeting A., Koester M., el Baradi T., Nietfeld W.,
RA   Bouwmeester T., Pieler T.;
RT   "Evolutionary conserved modules associated with zinc fingers in Xenopus
RT   laevis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:6097-6100(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 279-391.
RX   PubMed=2509712; DOI=10.1016/0022-2836(89)90155-1;
RA   Nietfeld W., El-Baradi T., Mentzel H., Pieler T., Koester M., Poeting A.,
RA   Knoechel W.;
RT   "Second-order repeats in Xenopus laevis finger proteins.";
RL   J. Mol. Biol. 208:639-659(1989).
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; M25867; AAA50014.1; -; mRNA.
DR   PIR; B33282; B33282.
DR   PIR; S06547; S06547.
DR   AlphaFoldDB; P18752; -.
DR   SMR; P18752; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd07765; KRAB_A-box; 1.
DR   InterPro; IPR001909; KRAB.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 3.
DR   SMART; SM00355; ZnF_C2H2; 4.
DR   SUPFAM; SSF57667; SSF57667; 3.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           <1..>391
FT                   /note="Oocyte zinc finger protein XlCOF7.2"
FT                   /id="PRO_0000047812"
FT   ZN_FING         284..306
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         312..334
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         340..362
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         368..391
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   NON_TER         1
FT   NON_TER         391
SQ   SEQUENCE   391 AA;  43535 MW;  A792A157A14D47CD CRC64;
     DDGGALHAPG SVIQKENNKN DKKILELMSN IIQLLTGEVA IRTHHVSIYF SLDEWDYITG
     NKDLYEEGMK EEPQQLHPLA ACEYKDESNV AAHTEATLCC NNDGNFTEMS PVEQPPPANG
     IKEEVASWEG GNQSDCSINK CTEQIQGTDT PTPIMGYRMN NSLLENYISN AIKEETASCE
     EINQSNCSIN PLTEQIQGTD TPTPIMGYSL FRIPCNKSDE SADTSPHKSR ITKKTLHKKN
     SCVVSHKITP IGEKPVSTSG CGKYFMKSSE LSVHPRTHTG EKPFPCSECG KCFINQSTLA
     RHYRTHTGEK PYPCSECGKC FASSTYLRDH RRIHTGEKLS SCSECGKYFL NCWSLARHHR
     THTGEKPYSC SECGKSFAIS SDLAGHRRRT H