ID   ZO84_XENLA              Reviewed;         780 AA.
AC   P18753;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Oocyte zinc finger protein XlCOF8.4;
DE   Flags: Fragment;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 1-272.
RX   PubMed=2503827; DOI=10.1073/pnas.86.16.6097;
RA   Knoechel W., Poeting A., Koester M., el Baradi T., Nietfeld W.,
RA   Bouwmeester T., Pieler T.;
RT   "Evolutionary conserved modules associated with zinc fingers in Xenopus
RT   laevis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:6097-6100(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 245-780.
RX   PubMed=2509712; DOI=10.1016/0022-2836(89)90155-1;
RA   Nietfeld W., El-Baradi T., Mentzel H., Pieler T., Koester M., Poeting A.,
RA   Knoechel W.;
RT   "Second-order repeats in Xenopus laevis finger proteins.";
RL   J. Mol. Biol. 208:639-659(1989).
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; M25868; AAA50015.1; -; mRNA.
DR   PIR; C33282; C33282.
DR   PIR; S06548; S06548.
DR   AlphaFoldDB; P18753; -.
DR   SMR; P18753; -.
DR   PRIDE; P18753; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 12.
DR   SMART; SM00355; ZnF_C2H2; 15.
DR   SUPFAM; SSF57667; SSF57667; 8.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 15.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 15.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           <1..>780
FT                   /note="Oocyte zinc finger protein XlCOF8.4"
FT                   /id="PRO_0000047813"
FT   ZN_FING         250..272
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         278..300
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         306..328
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         334..356
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         362..384
FT                   /note="C2H2-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         390..412
FT                   /note="C2H2-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         418..440
FT                   /note="C2H2-type 7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         446..468
FT                   /note="C2H2-type 8"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         474..496
FT                   /note="C2H2-type 9"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         618..640
FT                   /note="C2H2-type 10"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         646..668
FT                   /note="C2H2-type 11"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         674..696
FT                   /note="C2H2-type 12"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         702..724
FT                   /note="C2H2-type 13"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         730..752
FT                   /note="C2H2-type 14"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         758..780
FT                   /note="C2H2-type 15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   NON_TER         1
FT   NON_TER         780
SQ   SEQUENCE   780 AA;  88649 MW;  48E8C5BEFC9B3915 CRC64;
     ERMVNLTLEM IYLLTGEHYI PRKKSDDGGA LHAPGSVIQK ENNKNDKKIL ELMSNIIQLL
     TGEVAIRTGH VSIYFSLDEW DYIKGNKDLY EEGIKEEPQQ PLPPDCEYED KSDITADLGG
     TLYNYNEPSK IRAEGGDFCA NGNPTNPEIS PMKQPPPANG IKEEVASCDG GRQSDCSINP
     LTEQIQGTDI PTPIMGYNHL IIQAIKDNEN TSPHESRFDR HHTTHTTEKQ FSHHINLHND
     LSIHAGKKPF PCSECGKCFA GSSELNVHRR THTRVKPFSC SQCGKCFSNQ TKLKYHHRTH
     TGEKPFSCSE CGKCFSTPHV RARHQKTHTG EKPFPCSECG KCFARSSDVT VHRRTHTGEK
     PYSCSQCGKC FTRSSDLNVH RRTHTGEKPY SCSHCGKCFT TSSELNVHRR THTGEKPYSC
     SECGKSFPTS SEFTSHWKTH MEEKPFSCVQ CGKCFSKDTH LKYHYRTHTG EKPFSCFECG
     KCFTHNGSLK VHLKIHKREA DFCSKGNLTN PEISPVEHYP PTNEIKEEAT SWEEGNQSDY
     SINSLTEQIQ GPYTPTPIME YNHLIMQDNK YDVNACHSPL QETDVTKHAL HKRDIDRRQR
     TQTQLKYDHR TNTGDKPLSC SECGKCFSTY HVLARHQKTH TGEKPFSCSE CEKCYARSSD
     LNVHRRTHTG EKPYSCSECG KCFTRSSDFN VHRRTHTGEK PYSCSECGRC FPTSSVLTSH
     WRTHTGEKPF SCTECGKCFS RETYLKYHHR THTGEKPFSC SECGKCFTCN SSLKVHFQLH