ZPBP1_CHICK
ID ZPBP1_CHICK Reviewed; 320 AA.
AC Q6Q2W4;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 67.
DE RecName: Full=Zona pellucida-binding protein 1;
DE Flags: Fragment;
GN Name=ZPBP1;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Testis;
RA Lin Y.-N., Yan W., Burns K., Matzuk M.M.;
RT "Characterization of zona pellucida binding protein 2 (ZPBP2), a paralog of
RT ZPBP1.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in sperm morphogenesis and in sperm-oocyte
CC interaction during fertilization. {ECO:0000250|UniProtKB:Q62522}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}. Cytoplasmic vesicle,
CC secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:Q62522};
CC Peripheral membrane protein {ECO:0000250|UniProtKB:Q62522}.
CC -!- SIMILARITY: Belongs to the zona pellucida-binding protein Sp38 family.
CC {ECO:0000305}.
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DR EMBL; AY563140; AAS66455.1; -; mRNA.
DR AlphaFoldDB; Q6Q2W4; -.
DR STRING; 9031.ENSGALP00000036290; -.
DR PaxDb; Q6Q2W4; -.
DR VEuPathDB; HostDB:geneid_404537; -.
DR eggNOG; ENOG502RJ20; Eukaryota.
DR InParanoid; Q6Q2W4; -.
DR PhylomeDB; Q6Q2W4; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0002080; C:acrosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0001669; C:acrosomal vesicle; IBA:GO_Central.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0002199; C:zona pellucida receptor complex; IBA:GO_Central.
DR GO; GO:0001675; P:acrosome assembly; IBA:GO_Central.
DR GO; GO:0007339; P:binding of sperm to zona pellucida; IBA:GO_Central.
DR InterPro; IPR010857; Sp38-bd.
DR PANTHER; PTHR15443; PTHR15443; 1.
DR Pfam; PF07354; Sp38; 1.
PE 2: Evidence at transcript level;
KW Cytoplasmic vesicle; Glycoprotein; Membrane; Reference proteome; Secreted.
FT CHAIN <1..320
FT /note="Zona pellucida-binding protein 1"
FT /id="PRO_0000188983"
FT CARBOHYD 85
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 158
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT NON_TER 1
SQ SEQUENCE 320 AA; 35964 MW; 9923720C0A5FF619 CRC64;
GGLLLLGLLI VLLQAAPAVQ CLRSAESRSN SLKIVGSILF PVKVYVKLDH SSPHILCVTN
RLRNSELIDP VFRWNGPSGY LSSANSSVQI SPTGTLILGH FRSDLSGVYT CSLVYKLIAA
QPDKRLTIKY HIYAYSDPQY YYELTVQYHA APCNSFHNTS FGRALLQILS KLVADLSCEV
SLIKSECHHV KMQRGGLQSE MFFKFSVTCL DTENNKLCRQ SACDKPHRLH KAKDLIERFF
KREVEIRKKS TEPLPEIYYI EGTLQMVWVD RCYPGYGINA VRHPDCPECC VICSPRSYNP
SNGIHCLQCD TSLIYGATTC