ID   ZPBP2_CHICK             Reviewed;         352 AA.
AC   Q6PVW7;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Zona pellucida-binding protein 2;
DE   Flags: Precursor;
GN   Name=ZPBP2;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Testis;
RA   Lin Y.-N., Yan W., Burns K., Matzuk M.M.;
RT   "Characterization of zona pellucida binding protein 2 (ZPBP2), a paralog of
RT   ZPBP1.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be implicated in the gamete interaction during
CC       fertilization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Cytoplasmic vesicle,
CC       secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q6X786}.
CC   -!- SIMILARITY: Belongs to the zona pellucida-binding protein Sp38 family.
CC       {ECO:0000305}.
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DR   EMBL; AY575015; AAS68636.1; -; mRNA.
DR   RefSeq; NP_996870.1; NM_206987.1.
DR   AlphaFoldDB; Q6PVW7; -.
DR   STRING; 9031.ENSGALP00000021931; -.
DR   GeneID; 404532; -.
DR   KEGG; gga:404532; -.
DR   CTD; 124626; -.
DR   VEuPathDB; HostDB:geneid_404532; -.
DR   eggNOG; ENOG502R75S; Eukaryota.
DR   InParanoid; Q6PVW7; -.
DR   OrthoDB; 1069241at2759; -.
DR   PhylomeDB; Q6PVW7; -.
DR   PRO; PR:Q6PVW7; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.
DR   GO; GO:0044297; C:cell body; IEA:Ensembl.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0002199; C:zona pellucida receptor complex; IEA:Ensembl.
DR   GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0046466; P:membrane lipid catabolic process; IEA:Ensembl.
DR   GO; GO:0002638; P:negative regulation of immunoglobulin production; IEA:Ensembl.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:Ensembl.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR010857; Sp38-bd.
DR   PANTHER; PTHR15443; PTHR15443; 1.
DR   Pfam; PF07354; Sp38; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasmic vesicle; Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..352
FT                   /note="Zona pellucida-binding protein 2"
FT                   /id="PRO_0000041604"
FT   CARBOHYD        110
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        309
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   352 AA;  38750 MW;  26C9D65102E8AEA1 CRC64;
     MAGGGGRPCS PQRALLGMVA IMAVVAEARW GAPGRARAAP EEDQISVGFF RKNVIYGNVR
     RAENVYVKMF TNSPSLVCMD LSLSQEEIID PKYSWTGPDG RNLEGRGYAN LTGSGELMLV
     GFQESMSGAY TCTLSHRIIE TSAQEEVDVR DTYRFMVYAY REANHVYQVS VRFTAKGCEL
     AANARFVEEL KKIMESLISD LTCGVKGPSY RCHSLEAPHR GSPSELFITF QVNPFAPGWE
     DLCSRLPQDC EDTTNRRAQE ATERIGEFFR KQTYALKHQF QTVPTIHYVE GSFSVTPIDS
     CRPGFGRNNI THRSCAGCCV VCSPGTYSPD SAGSCRVCAG RRTAGYGAKS CP