ID   ZRAB2_CHICK             Reviewed;         334 AA.
AC   Q5ZLX5;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Zinc finger Ran-binding domain-containing protein 2;
GN   Name=ZRANB2 {ECO:0000250|UniProtKB:O95218}; ORFNames=RCJMB04_4i6;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1] {ECO:0000312|EMBL:CAG31268.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB {ECO:0000312|EMBL:CAG31268.1};
RC   TISSUE=Bursa of Fabricius {ECO:0000312|EMBL:CAG31268.1};
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May regulate alternative splicing by interfering with
CC       constitutive 5'-splice site selection. {ECO:0000250|UniProtKB:O95218}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O95218}.
CC   -!- DOMAIN: The RanBP2-type zinc fingers mediate binding to RNA.
CC       {ECO:0000250|UniProtKB:O95218}.
CC   -!- SIMILARITY: Belongs to the ZRANB2 family. {ECO:0000255}.
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DR   EMBL; AJ719609; CAG31268.1; -; mRNA.
DR   RefSeq; NP_001026468.1; NM_001031297.1.
DR   RefSeq; XP_015146542.1; XM_015291056.1.
DR   AlphaFoldDB; Q5ZLX5; -.
DR   SMR; Q5ZLX5; -.
DR   STRING; 9031.ENSGALP00000018494; -.
DR   PaxDb; Q5ZLX5; -.
DR   Ensembl; ENSGALT00000018517; ENSGALP00000018494; ENSGALG00000011340.
DR   GeneID; 424717; -.
DR   KEGG; gga:424717; -.
DR   CTD; 9406; -.
DR   VEuPathDB; HostDB:geneid_424717; -.
DR   eggNOG; KOG1995; Eukaryota.
DR   GeneTree; ENSGT00730000111078; -.
DR   HOGENOM; CLU_061048_0_0_1; -.
DR   InParanoid; Q5ZLX5; -.
DR   OMA; DLWGDNE; -.
DR   OrthoDB; 1399319at2759; -.
DR   PhylomeDB; Q5ZLX5; -.
DR   TreeFam; TF105996; -.
DR   PRO; PR:Q5ZLX5; -.
DR   Proteomes; UP000000539; Chromosome 8.
DR   Bgee; ENSGALG00000011340; Expressed in ovary and 12 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001530; F:lipopolysaccharide binding; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   InterPro; IPR001876; Znf_RanBP2.
DR   InterPro; IPR036443; Znf_RanBP2_sf.
DR   InterPro; IPR017337; ZRANB2.
DR   Pfam; PF00641; zf-RanBP; 2.
DR   PIRSF; PIRSF037956; UCP037956_ZnF_Ran; 1.
DR   SMART; SM00547; ZnF_RBZ; 2.
DR   SUPFAM; SSF90209; SSF90209; 2.
DR   PROSITE; PS01358; ZF_RANBP2_1; 2.
DR   PROSITE; PS50199; ZF_RANBP2_2; 2.
PE   2: Evidence at transcript level;
KW   Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat;
KW   RNA-binding; Zinc; Zinc-finger.
FT   CHAIN           1..334
FT                   /note="Zinc finger Ran-binding domain-containing protein 2"
FT                   /id="PRO_0000285986"
FT   ZN_FING         9..40
FT                   /note="RanBP2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00322"
FT   ZN_FING         65..94
FT                   /note="RanBP2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00322"
FT   REGION          117..334
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..132
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..181
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..199
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        258..283
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        296..313
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   334 AA;  37863 MW;  25FBFBEB8AD7F00F CRC64;
     MSTKNFRVSD GDWICPDKKC GNVNFARRTS CNRCGREKTT EAKMMKAGGT EIGKTLAEKS
     RGLFSANDWQ CKTCGNVNWA RRSECNMCNT PKYAKLEERT GYGGGFNERE NVEYIEREES
     DGEYDEFGRK KKKYRGKPVG PASILKEVED KESEGEDEED EDGDLSKYKL DEDEDEDDAD
     LSKYNLDASE EEDTNKKKKS NRRSRSKSRS SHSRSSSRSS SHSSSRSRSR SHSRSSSSSR
     SRSRSSSREH SRSRGSKSRS SSRSYRGSST PRKRSYSSSR SSSSPERSKK RSRSRSSSSG
     DRKKRRSRSR SPERRRRSSS GSSHSGSRTS SKKK