ID   ZRAP_ECO57              Reviewed;         141 AA.
AC   P0AAB0; P32682; Q8X6X2;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Zinc resistance-associated protein;
DE   Flags: Precursor;
GN   Name=zraP; OrderedLocusNames=Z5578, ECs4925;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Binds zinc. Could be an important component of the zinc-
CC       balancing mechanism (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG59199.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=BAB38348.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE005174; AAG59199.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BA000007; BAB38348.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_312952.2; NC_002695.1.
DR   RefSeq; WP_000828222.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AAB0; -.
DR   SMR; P0AAB0; -.
DR   STRING; 155864.EDL933_5333; -.
DR   EnsemblBacteria; AAG59199; AAG59199; Z5578.
DR   EnsemblBacteria; BAB38348; BAB38348; ECs_4925.
DR   GeneID; 58390060; -.
DR   GeneID; 915713; -.
DR   KEGG; ece:Z5578; -.
DR   KEGG; ecs:ECs_4925; -.
DR   PATRIC; fig|386585.9.peg.5150; -.
DR   eggNOG; COG3678; Bacteria.
DR   HOGENOM; CLU_124884_0_0_6; -.
DR   OMA; GMGYGDC; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   InterPro; IPR025961; Metal_resist.
DR   Pfam; PF13801; Metal_resist; 1.
PE   3: Inferred from homology;
KW   Periplasm; Reference proteome; Signal; Zinc.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000250"
FT   CHAIN           27..141
FT                   /note="Zinc resistance-associated protein"
FT                   /id="PRO_0000041881"
SQ   SEQUENCE   141 AA;  15199 MW;  392A8B29CEBECC1B CRC64;
     MKRNTKIALV MMALSAMAMG STSAFAHGGH GMWQQNAAPL TSEQQTAWQK IHNDFYAQSS
     ALQQQLVTKR YEYNALLAAN PPDSSKINAV AKEMENLRQS LDELRVKRDI AMAEAGIPRG
     AGMGMGYGGC GGGGHMGMGH W