ID   ZRAP_SHIFL              Reviewed;         141 AA.
AC   P0AAB1; P32682; Q8X6X2;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Zinc resistance-associated protein;
DE   Flags: Precursor;
GN   Name=zraP; OrderedLocusNames=SF4074, S3661;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Binds zinc. Could be an important component of the zinc-
CC       balancing mechanism (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZraP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN45503.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAP18698.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE005674; AAN45503.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE014073; AAP18698.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_709796.3; NC_004337.2.
DR   RefSeq; WP_000828222.1; NZ_WPGW01000040.1.
DR   AlphaFoldDB; P0AAB1; -.
DR   SMR; P0AAB1; -.
DR   STRING; 198214.SF4074; -.
DR   EnsemblBacteria; AAN45503; AAN45503; SF4074.
DR   EnsemblBacteria; AAP18698; AAP18698; S3661.
DR   GeneID; 1027536; -.
DR   GeneID; 58390060; -.
DR   KEGG; sfl:SF4074; -.
DR   KEGG; sfx:S3661; -.
DR   PATRIC; fig|198214.7.peg.4798; -.
DR   HOGENOM; CLU_124884_0_0_6; -.
DR   OrthoDB; 1874113at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   InterPro; IPR025961; Metal_resist.
DR   Pfam; PF13801; Metal_resist; 1.
PE   3: Inferred from homology;
KW   Periplasm; Reference proteome; Signal; Zinc.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000250"
FT   CHAIN           27..141
FT                   /note="Zinc resistance-associated protein"
FT                   /id="PRO_0000041885"
SQ   SEQUENCE   141 AA;  15199 MW;  392A8B29CEBECC1B CRC64;
     MKRNTKIALV MMALSAMAMG STSAFAHGGH GMWQQNAAPL TSEQQTAWQK IHNDFYAQSS
     ALQQQLVTKR YEYNALLAAN PPDSSKINAV AKEMENLRQS LDELRVKRDI AMAEAGIPRG
     AGMGMGYGGC GGGGHMGMGH W