ZRAS1_MOUSE
ID ZRAS1_MOUSE Reviewed; 213 AA.
AC Q8R0E5; Q9DA28;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 18-MAR-2008, sequence version 2.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Putative uncharacterized protein ZNRD1-AS1;
DE AltName: Full=T-complex testis-expressed protein 4;
DE AltName: Full=ZNRD1 antisense RNA 1;
DE AltName: Full=ZNRD1 antisense gene protein 1;
GN Name=Znrd1-as; Synonyms=Tctex4, Znrd1as;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=1718647; DOI=10.1002/dvg.1020120409;
RA Ha H., Howard C.A., Yeom Y.I., Abe K., Uehara H., Artzt K., Bennett D.;
RT "Several testis-expressed genes in the mouse T-complex have expression
RT differences between wild-type and t-mutant mice.";
RL Dev. Genet. 12:318-332(1991).
CC -!- FUNCTION: May be involved in male sterility.
CC {ECO:0000269|PubMed:1718647}.
CC -!- TISSUE SPECIFICITY: Specifically expressed in testis.
CC {ECO:0000269|PubMed:1718647}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH27007.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAB24473.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAB24473.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AK006236; BAB24473.1; ALT_SEQ; mRNA.
DR EMBL; BC027007; AAH27007.1; ALT_INIT; mRNA.
DR CCDS; CCDS89093.1; -.
DR RefSeq; NP_083878.1; NM_029602.1.
DR AlphaFoldDB; Q8R0E5; -.
DR STRING; 10090.ENSMUSP00000048695; -.
DR PaxDb; Q8R0E5; -.
DR PRIDE; Q8R0E5; -.
DR Ensembl; ENSMUST00000173814; ENSMUSP00000134016; ENSMUSG00000036214.
DR GeneID; 76416; -.
DR KEGG; mmu:76416; -.
DR UCSC; uc008clq.1; mouse.
DR CTD; 76416; -.
DR MGI; MGI:1923666; Znrd1as.
DR VEuPathDB; HostDB:ENSMUSG00000036214; -.
DR eggNOG; ENOG502TFIF; Eukaryota.
DR GeneTree; ENSGT00390000016534; -.
DR HOGENOM; CLU_1437546_0_0_1; -.
DR InParanoid; Q8R0E5; -.
DR OMA; GIQNAQR; -.
DR OrthoDB; 1176284at2759; -.
DR PhylomeDB; Q8R0E5; -.
DR TreeFam; TF337245; -.
DR BioGRID-ORCS; 76416; 0 hits in 69 CRISPR screens.
DR PRO; PR:Q8R0E5; -.
DR Proteomes; UP000000589; Chromosome 17.
DR RNAct; Q8R0E5; protein.
DR Bgee; ENSMUSG00000036214; Expressed in seminiferous tubule of testis and 225 other tissues.
DR ExpressionAtlas; Q8R0E5; baseline and differential.
DR Genevisible; Q8R0E5; MM.
DR InterPro; IPR040005; ZNRD1-AS1.
DR PANTHER; PTHR41403; PTHR41403; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..213
FT /note="Putative uncharacterized protein ZNRD1-AS1"
FT /id="PRO_0000324092"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 21
FT /note="P -> Q (in Ref. 1; BAB24473)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 213 AA; 25489 MW; 38026389161CEAB3 CRC64;
MVERMKKDTG DETKTKVQEE PPSPSPPPPP PPRRERQKQH YWVPEREKKQ IERHIHRTSH
AREFTDKPWR QPRLFSETTL PKIVLEEESI PQAQKRRQAH ERELLQIKDH RERMIRGREL
LQQRLKDRIL RKSPSQIPLP EKRDQVKKQK KEFEKVVAYP LVQPSCTSRI KVDVLMEKSQ
DEEDLSTIIK PFGRRFLAVP PFLRTQIGKI KDL
