ID   ZRG8_ASHGO              Reviewed;         991 AA.
AC   Q755T2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Zinc-regulated protein 8;
GN   Name=ZRG8; OrderedLocusNames=AER436C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in maintenance of polarized growth and daughter-
CC       cell-specific transcription. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Bud {ECO:0000250}. Bud
CC       neck {ECO:0000250}. Bud tip {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZRG8 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE016818; AAS53115.1; -; Genomic_DNA.
DR   RefSeq; NP_985291.1; NM_210645.1.
DR   AlphaFoldDB; Q755T2; -.
DR   STRING; 33169.AAS53115; -.
DR   EnsemblFungi; AAS53115; AAS53115; AGOS_AER436C.
DR   GeneID; 4621511; -.
DR   KEGG; ago:AGOS_AER436C; -.
DR   eggNOG; ENOG502QSM8; Eukaryota.
DR   HOGENOM; CLU_301677_0_0_1; -.
DR   InParanoid; Q755T2; -.
DR   OMA; QSLKYHD; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR   GO; GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Zinc.
FT   CHAIN           1..991
FT                   /note="Zinc-regulated protein 8"
FT                   /id="PRO_0000333502"
FT   REGION          1..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          68..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          165..192
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          306..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          516..546
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          564..588
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          603..631
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          847..866
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..33
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        516..533
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        566..581
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   991 AA;  109062 MW;  82138269AAC44047 CRC64;
     MRTFIKSHRR SSSLEACPPK TTPKRNSTGS PTELQPPVFP PSAPRQSSSF ESLQKLTSGK
     LFSTKLFKKS GAQKLPATPD LPAFPRGYDS RSPSCEWRAL GTEVALEDIP AIKGTRTHEW
     GENSDVSNSV IVLNRNSISS DGSYVETRDE QSPWRLARRS LDSATQTLSS TEEYSGPEIR
     IRSSTPHKLR EASDSFLKKR WNRQARIHSK ADIAKLEGSF PMPVEAISPP FARRRSSERS
     QCLGASGTME QQLNPVNPEK CSLYAACSER SQSLTKATHA LVATASTEVG LQNNLNSASV
     ELRDDLENER ESLSEEDSGS SFSDDSSKFS FEVGGGINGR TSSVKYYSKP DPPMRNYIDD
     LFEDEDFDED MNCYDDDQEY EEDTEHLFGA SHVQLEHGYS MMHEVTDSDS EQETKSNISS
     VLSKGQNAIF PSSDGRFVLN SGDSNGGSNQ ENIGVKMLEK SISNIGLEDV EDVEDDSDGI
     IPTDTQEDID SPVHSQPSHA NFSHIKKYSD IFGISDSDED TANNSSSQYP FEEGYYSSDE
     EPTLRAEPAA NTEDGFTDAL KASFKQDESS HSSTDSIDKT PTFALDTDGE YFPPTLTLNK
     KSEVDDLDVS EEAAPESISL STSDLEQPAD AKQDRANIIS SSIMDYAIHE VATTESVESD
     ENQTTCVPQT TRVPSKVTKY ADLFNLSDEN DEDGSDGEFL DDMGFNELES TPVESKKPNI
     PPRRLGNEYF GNFHSPVASS HNAPAVPRQH SPLSAKVILP ATENTSIKSQ YAVPRMGQSP
     LPPPARSQTL KFHDLHSSLD GEIRGTMSNL FFIDESEEDQ YYQVQSKVDD DYLDEINNVP
     EDFNFSDNDS DTCSGKSPMF PTGLRNSFRK TRSFSEKPTG LAKEPTPTRY KLDIKNKTVT
     FFKNGLSRPL SEGSLHGQSI PSRAHVPPLS LRKAMSEGSL EQSAHSPLGY GSLAFGLNSL
     KSPEMSRTDA YGLSPIQEAI SSGDASPKLV N