ID   ZRG8_VANPO              Reviewed;         859 AA.
AC   A7TR87;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Zinc-regulated protein 8;
GN   Name=ZRG8; ORFNames=Kpol_423p10;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Involved in maintenance of polarized growth and daughter-
CC       cell-specific transcription. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Bud {ECO:0000250}. Bud
CC       neck {ECO:0000250}. Bud tip {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZRG8 family. {ECO:0000305}.
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DR   EMBL; DS480472; EDO15220.1; -; Genomic_DNA.
DR   RefSeq; XP_001643078.1; XM_001643028.1.
DR   AlphaFoldDB; A7TR87; -.
DR   SMR; A7TR87; -.
DR   STRING; 436907.A7TR87; -.
DR   EnsemblFungi; EDO15220; EDO15220; Kpol_423p10.
DR   GeneID; 5543296; -.
DR   KEGG; vpo:Kpol_423p10; -.
DR   eggNOG; ENOG502QSM8; Eukaryota.
DR   HOGENOM; CLU_301677_0_0_1; -.
DR   InParanoid; A7TR87; -.
DR   OMA; QSLKYHD; -.
DR   OrthoDB; 1554991at2759; -.
DR   PhylomeDB; A7TR87; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR   GO; GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Zinc.
FT   CHAIN           1..859
FT                   /note="Zinc-regulated protein 8"
FT                   /id="PRO_0000333506"
FT   REGION          1..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          296..374
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          722..758
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          776..859
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..330
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        341..355
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        724..745
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        776..792
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        793..815
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        841..859
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   859 AA;  96632 MW;  026E1694A1282631 CRC64;
     MRSFIKSHKN SNSLDGSQSR WNNSEVPNVQ RSSADSFNYS GSTVISSNSN TVTSMSIPNN
     LPNSKNYSPK HTPSFESFHR LANKIPSKLF KKSSNNALNA TYNNSLHLGE SLSSPPTPRT
     INTSTDAIQK VRSTESEIEI PSIKGTITHS WGTRSDTGGH SIIVLNEPRS SLSGASNSDY
     SDLEPAARIS GLKRPSIVSI KTNNSFEEYN STPIITEEED LKNFDSKIIN PSTPNDINAV
     KYNNRKTQII GNENLFRTSN LQNKVRKHFI SPLENLNENV LEADNKQGVV ENVQRKKKVP
     NLNASPQDTI DGNRSRTISF AETSKTLPQM EGASDADGES DSCSETTDDD DDDNTSKFSF
     EYNRPNGRTA SMKYYSKPEP VNNIYIDDLY EDENFDENMN YDEDSLDGFE FPSNKFDYGN
     ENSDENDDIQ GHENYVVQDN NSSKGPKLKS EAPKKVQTYN DLFDLSDDFD YDPSDEYQNE
     TRLIHEMCED GEASQIDNMM VDENIISPQK SLTSSKSFNN SNVSKSSPLI KPLETPKKKI
     IVKPVASFAD IFNLDDEEDR DFKDDDSCND ESDGEYVLKD PFNIPGGKNL LNRHKSLKKN
     SSFSLKKIPS NGDSIDNNLM DKKLDKYIVD INKSIKKHSD IPDLHFVPPD NSSDIILPKR
     SQSLKYHDLS SILDSDVPGS TRDLFFIDEA EEDSYNVKHG LTEEEYLDEI NNVPEDFYFS
     DSEQDMSPMK SPFRRSNTGS FRRTHSFSGK PIGAAKDNTP VKSKLEIKNK TVTFFNHPWT
     PNSQSGFSGK SPKKSIKKTD NLENSEEEHL LATPKRDDSS AYGFSTPDRQ FRKPTPEYLQ
     DYSLSPIQEG YSSVDNSPR