ZSA5D_HUMAN
ID ZSA5D_HUMAN Reviewed; 497 AA.
AC P0CG00;
DT 18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT 18-MAY-2010, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Putative zinc finger and SCAN domain-containing protein 5D {ECO:0000312|HGNC:HGNC:37706};
DE AltName: Full=Zinc finger and SCAN domain-containing protein 5D pseudogene {ECO:0000312|HGNC:HGNC:37706};
GN Name=ZSCAN5DP {ECO:0000312|HGNC:HGNC:37706};
GN Synonyms=ZSCAN5D {ECO:0000312|HGNC:HGNC:37706};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AC011506; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; P0CG00; -.
DR SMR; P0CG00; -.
DR STRING; 9606.ENSP00000470691; -.
DR iPTMnet; P0CG00; -.
DR PhosphoSitePlus; P0CG00; -.
DR BioMuta; HGNC:37706; -.
DR DMDM; 296439806; -.
DR jPOST; P0CG00; -.
DR MassIVE; P0CG00; -.
DR MaxQB; P0CG00; -.
DR PaxDb; P0CG00; -.
DR PeptideAtlas; P0CG00; -.
DR PRIDE; P0CG00; -.
DR UCSC; uc061del.1; human.
DR GeneCards; ZSCAN5DP; -.
DR HGNC; HGNC:37706; ZSCAN5DP.
DR neXtProt; NX_P0CG00; -.
DR eggNOG; KOG1721; Eukaryota.
DR InParanoid; P0CG00; -.
DR PhylomeDB; P0CG00; -.
DR PathwayCommons; P0CG00; -.
DR Pharos; P0CG00; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; P0CG00; protein.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd07936; SCAN; 1.
DR Gene3D; 1.10.4020.10; -; 1.
DR InterPro; IPR003309; SCAN_dom.
DR InterPro; IPR038269; SCAN_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF02023; SCAN; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR SMART; SM00431; SCAN; 1.
DR SMART; SM00355; ZnF_C2H2; 5.
DR SUPFAM; SSF57667; SSF57667; 3.
DR PROSITE; PS50804; SCAN_BOX; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 5.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE 5: Uncertain;
KW Metal-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..497
FT /note="Putative zinc finger and SCAN domain-containing
FT protein 5D"
FT /id="PRO_0000394247"
FT DOMAIN 41..123
FT /note="SCAN box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00187"
FT ZN_FING 352..374
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 380..402
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 408..430
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 436..458
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 464..486
FT /note="C2H2-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT REGION 148..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..227
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 56244 MW; 20D84F8098CEF308 CRC64;
MGQCRNWKWG LESFDFSINR RSSAPGQLES ASQMRESWRH KAGRRMFSCP EESDPIQALR
KLTELCHLWL RPDLHTKEQI LDMLVMEQFM ISMPQELQVL VKVNGVQSCK DLEDLLRNNR
RPKKWSVVNF LGKEYLMQES DVEMAEIPAS VRDDPRGVSS QRASSVNEMR PGEGQASQEL
QTLPRVPALS RRQEEDFLLP ETTVMKSAPK ALRPKPTLEK DLNVDREENT GLTSPEPQLP
NGPSVVGAKE GKEPKKRASV ENVDADTPSA CVVEREASTH SGSRGDALNL RCPKRSKPDA
TSISQEGPQG GATPVGNSES PGKPEINSVY SPGPAGAVSH PNGQEAKELL PFACGVCNKR
FTCNSKLAIH MRSHTGERPF QCNFCERCFT QLSDLRVHQR IHTGEKPYTC DICHKRFNRM
FSLKCHKRSH TGEKPYKCKD CNQVFTYRKN LNEHKLIHSG EKPYKCPKCL RAFRRPETLK
YHQKTHQETT APRECEG
