ZSWM1_MOUSE
ID ZSWM1_MOUSE Reviewed; 455 AA.
AC Q9CWV7; A2A5J3; Q8R163;
DT 25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Zinc finger SWIM domain-containing protein 1;
GN Name=Zswim1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Embryonic stem cell;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Brain, and Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH25184.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK010358; BAB26878.1; -; mRNA.
DR EMBL; AL591495; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC025184; AAH25184.1; ALT_INIT; mRNA.
DR EMBL; BC046831; AAH46831.1; -; mRNA.
DR CCDS; CCDS17059.1; -.
DR RefSeq; NP_082304.1; NM_028028.2.
DR AlphaFoldDB; Q9CWV7; -.
DR PhosphoSitePlus; Q9CWV7; -.
DR EPD; Q9CWV7; -.
DR MaxQB; Q9CWV7; -.
DR PaxDb; Q9CWV7; -.
DR PRIDE; Q9CWV7; -.
DR ProteomicsDB; 275108; -.
DR Antibodypedia; 27817; 79 antibodies from 16 providers.
DR DNASU; 71971; -.
DR Ensembl; ENSMUST00000017908; ENSMUSP00000017908; ENSMUSG00000017764.
DR GeneID; 71971; -.
DR UCSC; uc008nwi.1; mouse.
DR CTD; 90204; -.
DR MGI; MGI:1919221; Zswim1.
DR VEuPathDB; HostDB:ENSMUSG00000017764; -.
DR eggNOG; ENOG502RNJT; Eukaryota.
DR GeneTree; ENSGT00390000017273; -.
DR HOGENOM; CLU_563302_0_0_1; -.
DR InParanoid; Q9CWV7; -.
DR OMA; QSCFMQG; -.
DR OrthoDB; 338340at2759; -.
DR PhylomeDB; Q9CWV7; -.
DR TreeFam; TF335703; -.
DR BioGRID-ORCS; 71971; 1 hit in 72 CRISPR screens.
DR ChiTaRS; Zswim1; mouse.
DR PRO; PR:Q9CWV7; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q9CWV7; protein.
DR Bgee; ENSMUSG00000017764; Expressed in embryonic brain and 248 other tissues.
DR ExpressionAtlas; Q9CWV7; baseline and differential.
DR Genevisible; Q9CWV7; MM.
DR GO; GO:0005634; C:nucleus; IDA:MGI.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR InterPro; IPR045563; DUF5909.
DR InterPro; IPR007527; Znf_SWIM.
DR InterPro; IPR040303; ZSWIM1.
DR PANTHER; PTHR31569:SF0; PTHR31569:SF0; 1.
DR Pfam; PF19286; DUF5909; 1.
DR Pfam; PF04434; SWIM; 1.
DR PROSITE; PS50966; ZF_SWIM; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..455
FT /note="Zinc finger SWIM domain-containing protein 1"
FT /id="PRO_0000223096"
FT ZN_FING 333..375
FT /note="SWIM-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00325"
FT REGION 264..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 455 AA; 51481 MW; 201886B814EB9CFF CRC64;
MALTMLNGLL IKDSSPPMLH QISKTPQLDA FNYQSCFMQD LFAHFPEVLF IHRTYNPRGK
VLYTFLVDGP RVQVEGPLAR AVYFAIPTNE DARGLAQMFQ VFKKFNPAWE RVNTILVDPH
FLLLPTLTME FPTAEVLLSA FHICKFLQGK FYQLPLEQPV QRLLLSSLQS TMCSATAGNL
RKLYTLLNNC IPSSRLPELH SHWLLNDRIW LAHRWRSRAQ SSRYFQSLEI MAHILSQFFG
TTPFEKQGMA SVFRYMQQNS SDKASLSLAE TPQDSHTPSE ASAENPNTEQ LVEARIQHSL
NAICTGPAAQ LCLGELAVVQ KSMHLIGSGS EKMSIQILED THTVQPQPPA SCSCYFNQAF
HLPCRHILAM LSARQQVLQP DMLPAQWTSG CASSLDSILG SKWSASLDKH LAVTLLTEEV
GRLLQHCSEE EFERRYSTLR ELADNWIGPY EQVQL
