ZSWM5_MOUSE
ID ZSWM5_MOUSE Reviewed; 1188 AA.
AC Q80TC6;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 16-JAN-2004, sequence version 2.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Zinc finger SWIM domain-containing protein 5;
GN Name=Zswim5; Synonyms=Kiaa1511;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=12693553; DOI=10.1093/dnares/10.1.35;
RA Okazaki N., Kikuno R., Ohara R., Inamoto S., Aizawa H., Yuasa S.,
RA Nakajima D., Nagase T., Ohara O., Koga H.;
RT "Prediction of the coding sequences of mouse homologues of KIAA gene: II.
RT The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs
RT identified by screening of terminal sequences of cDNA clones randomly
RT sampled from size-fractionated libraries.";
RL DNA Res. 10:35-48(2003).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK122519; BAC65801.1; -; mRNA.
DR CCDS; CCDS18520.1; -.
DR RefSeq; NP_001025083.1; NM_001029912.2.
DR AlphaFoldDB; Q80TC6; -.
DR BioGRID; 216770; 1.
DR STRING; 10090.ENSMUSP00000049474; -.
DR iPTMnet; Q80TC6; -.
DR PhosphoSitePlus; Q80TC6; -.
DR EPD; Q80TC6; -.
DR PaxDb; Q80TC6; -.
DR PRIDE; Q80TC6; -.
DR ProteomicsDB; 275317; -.
DR Antibodypedia; 2902; 76 antibodies from 16 providers.
DR Ensembl; ENSMUST00000044823; ENSMUSP00000049474; ENSMUSG00000033948.
DR GeneID; 74464; -.
DR KEGG; mmu:74464; -.
DR UCSC; uc008uhq.1; mouse.
DR CTD; 57643; -.
DR MGI; MGI:1921714; Zswim5.
DR VEuPathDB; HostDB:ENSMUSG00000033948; -.
DR eggNOG; KOG3615; Eukaryota.
DR GeneTree; ENSGT00940000158362; -.
DR HOGENOM; CLU_005301_1_0_1; -.
DR InParanoid; Q80TC6; -.
DR OMA; DTGDCDP; -.
DR OrthoDB; 58074at2759; -.
DR PhylomeDB; Q80TC6; -.
DR TreeFam; TF324881; -.
DR BioGRID-ORCS; 74464; 1 hit in 72 CRISPR screens.
DR ChiTaRS; Zswim5; mouse.
DR PRO; PR:Q80TC6; -.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; Q80TC6; protein.
DR Bgee; ENSMUSG00000033948; Expressed in medial ganglionic eminence and 135 other tissues.
DR Genevisible; Q80TC6; MM.
DR GO; GO:0031462; C:Cul2-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR InterPro; IPR007527; Znf_SWIM.
DR PROSITE; PS50966; ZF_SWIM; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..1188
FT /note="Zinc finger SWIM domain-containing protein 5"
FT /id="PRO_0000223104"
FT ZN_FING 222..259
FT /note="SWIM-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00325"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 123..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1188 AA; 130927 MW; DBC36266CE4E4536 CRC64;
MAEGGEREEL LSPPPISPAK RLCSWPSPQA HHPRGTPGAA GGGAGGGGGG CLAPGARPHL
QPESLLDCAA KTVAEKWAYE RVEERFERIP EPVQRRIVYW SFPRNEREIC MYSSFQYRGG
PGAGAAAGAA GASPVEEGPP PPPGAAAPAG SAPGAAGAGS SPGLGAGTGT ASGGCGGGEG
LPFRRGIRLL DSGSVENVLQ VGFHLSGTVT EPAMASEPAV TYKVAISFDR CKITSVSCGC
GNKDIFYCAH VVALSLYRIR KPDQVKLRLP ISETLFQMNR DQLQKFIQYL ITAHHTEVLP
TAQKLADEIL SSNSEINQVN GAPDPTAGAS IDDENCWHLD EEQVKEQVKL FLSQGGYYGS
GKQLNSMFAK VREMLRMRDS NGARMLTLIT EQFMADPRLT LWRQQGTSMT DKCRQLWDEL
GALWVCIILN PHCKLEEKSC WLQQLQKWSD LDICPLEDGN YGHELPNITN ALSQSASHSP
DSLSRPRRTV FTRAIEGREL HWQDSHLQRI ISSGIYTAPA CQRENERLLF NSHGQPLWLE
HVPTACARVD ALRSHGYPKE ALRLTVAIIN TLRLQQQRQL EIYKHQKKEL LQRGTTTITN
LEGWVGHPLD PIGCLFLTLT EACRLNDDSY MEMSDMNESR LPVYQHVPVA SGCPNSNESY
LSLALEVALM GMGQQRVMPE GLYAQDKVCR NEEQLLSQLQ ELQLDDELVQ TLRKQCILLL
EGGPFSGLGE VIHRESVPMH TFAKYLFSAL LPHDPDLSYK LALRAMRLPV LENSSSAGDT
SHPHHMVSVV PSRYPRWFTL GHLESQQCEL ASTMLTAAKG DTLRLRTLLE AIQKHIHSPS
LIFKLAQDAF KIATPTDSST DGTLLNVALE LGLQVMRMTL STLNWRRREM VRWLVTCATE
VGVRALVSIL QSWYTLFTPT EATSIVAATA VSHTTILRLS LDYPQREELA SCARTLALQC
AMKDPQSCAL SALTLCEKDH IAFEAAYQIA IDAAAGGMTH SQLFTIARYM ELRGYPLRAF
KLASLAMSHL NLAYNQDTHP AINDVLWACA LSHSLGKNEL AALIPLVVKS VHCATVLSDI
LRRCTVTAPG LAGIPGRRSS GKLMSTDKAP LRQLLDATIN AYINTTHSRL THISPRHYGE
FIEFLSKARE TFLLPQDGHL QFAQFIDNLK QIYKGKKKLM LLVRERFG