ZSWM9_MOUSE
ID ZSWM9_MOUSE Reviewed; 447 AA.
AC Q6DI92; Q3TRL3; Q3V0S9; Q9D3B2;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Uncharacterized protein ZSWIM9;
GN Name=Zswim9 {ECO:0000312|MGI:MGI:2447816};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2; 3 AND 4).
RC STRAIN=C57BL/6J; TISSUE=Bone, Medulla oblongata, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=C57BL/6J; TISSUE=Eye;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=4;
CC Name=1;
CC IsoId=Q6DI92-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q6DI92-2; Sequence=VSP_031965;
CC Name=3;
CC IsoId=Q6DI92-3; Sequence=VSP_031966, VSP_031967, VSP_031968;
CC Name=4;
CC IsoId=Q6DI92-4; Sequence=VSP_031969, VSP_031970;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH75681.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAB31091.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAE35600.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AK018141; BAB31091.1; ALT_FRAME; mRNA.
DR EMBL; AK132923; BAE21424.1; -; mRNA.
DR EMBL; AK160064; BAE35600.1; ALT_FRAME; mRNA.
DR EMBL; AK162673; BAE37016.1; -; mRNA.
DR EMBL; BC075681; AAH75681.1; ALT_FRAME; mRNA.
DR RefSeq; NP_796286.2; NM_177312.4.
DR AlphaFoldDB; Q6DI92; -.
DR STRING; 10090.ENSMUSP00000104172; -.
DR PhosphoSitePlus; Q6DI92; -.
DR PaxDb; Q6DI92; -.
DR PRIDE; Q6DI92; -.
DR ProteomicsDB; 275163; -. [Q6DI92-1]
DR ProteomicsDB; 275164; -. [Q6DI92-2]
DR Antibodypedia; 68326; 15 antibodies from 8 providers.
DR DNASU; 321008; -.
DR GeneID; 321008; -.
DR KEGG; mmu:321008; -.
DR UCSC; uc009ffk.1; mouse. [Q6DI92-1]
DR UCSC; uc009ffm.1; mouse. [Q6DI92-4]
DR UCSC; uc009ffn.1; mouse. [Q6DI92-3]
DR CTD; 374920; -.
DR MGI; MGI:2447816; Zswim9.
DR VEuPathDB; HostDB:ENSMUSG00000070814; -.
DR eggNOG; ENOG502QUUY; Eukaryota.
DR HOGENOM; CLU_038227_0_0_1; -.
DR InParanoid; Q6DI92; -.
DR OrthoDB; 287340at2759; -.
DR PhylomeDB; Q6DI92; -.
DR TreeFam; TF337793; -.
DR BioGRID-ORCS; 321008; 4 hits in 33 CRISPR screens.
DR PRO; PR:Q6DI92; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q6DI92; protein.
DR ExpressionAtlas; Q6DI92; baseline and differential.
DR Genevisible; Q6DI92; MM.
DR GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IGI:MGI.
DR InterPro; IPR040854; DUF5575.
DR PANTHER; PTHR47086; PTHR47086; 1.
DR Pfam; PF17738; DUF5575; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..447
FT /note="Uncharacterized protein ZSWIM9"
FT /id="PRO_0000322597"
FT VAR_SEQ 1..206
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_031965"
FT VAR_SEQ 1
FT /note="M -> MVRPGGAAERQVERVSRGPRM (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_031966"
FT VAR_SEQ 93..117
FT /note="PPQPSCPAFITVKLSPLRDRLVVTE -> CVSLSCDPTGGGEQGVSQTASNP
FT QV (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_031967"
FT VAR_SEQ 118..447
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_031968"
FT VAR_SEQ 198..201
FT /note="KLVF -> GSHK (in isoform 4)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_031969"
FT VAR_SEQ 202..447
FT /note="Missing (in isoform 4)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_031970"
SQ SEQUENCE 447 AA; 50467 MW; 2AED23156EC587C0 CRC64;
MELTEPLPSA AVQKEEQELL DRTFFSWAEF SRFFDKWCQQ RLVVFSVKSS TRVARSPWAN
TPPLYRLIHV LKYSYVLLVC KDVRMPNKST AWPPQPSCPA FITVKLSPLR DRLVVTECQL
THSHPACPRE FAYHFRPGHL LANSCLPVRI TNQISKQFVA PADVRRLLTH CKGPDHGVLD
ALQVLEGLFR TDPEAKVKLV FVEDQAMVET VFLLTSRTRA LLRRFPRILL VDRLPGLQGT
LDLMAVLCVD SAGRARQAAC CVARPGTPSL LRFMLVSLLQ SAPDVKGRVR CLTAGPEVAG
QLRAVRQLLP CARVQICRAQ GLETLFSKAQ ELGGASQEDP DLWPLLCRLA DSKSYTAYSE
ALAELRSQAP TAFIRYFEHN WAPRHDMWVR FRAYEATRDL DACALVRSHR RRLLRRLSPS
HSVAQCLRDL VAMQWADATG EAALRGC
