ID   ZTF1_CAEEL              Reviewed;         582 AA.
AC   P34450; Q8IG18;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 2.
DT   03-AUG-2022, entry version 149.
DE   RecName: Full=Zinc finger transcription factor family protein 1;
GN   Name=ztf-1 {ECO:0000312|WormBase:F54F2.5};
GN   ORFNames=F54F2.5 {ECO:0000312|WormBase:F54F2.5};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; BX284603; CCD71238.1; -; Genomic_DNA.
DR   PIR; S44830; S44830.
DR   RefSeq; NP_498942.1; NM_066541.4.
DR   RefSeq; NP_871662.1; NM_181933.3.
DR   AlphaFoldDB; P34450; -.
DR   BioGRID; 41438; 8.
DR   IntAct; P34450; 5.
DR   STRING; 6239.F54F2.5a; -.
DR   PaxDb; P34450; -.
DR   PRIDE; P34450; -.
DR   EnsemblMetazoa; F54F2.5.1; F54F2.5.1; WBGene00018833.
DR   GeneID; 176236; -.
DR   KEGG; cel:CELE_F54F2.5; -.
DR   UCSC; F54F2.5a; c. elegans.
DR   CTD; 176236; -.
DR   WormBase; F54F2.5; CE25004; WBGene00018833; ztf-1.
DR   eggNOG; KOG1721; Eukaryota.
DR   HOGENOM; CLU_479170_0_0_1; -.
DR   InParanoid; P34450; -.
DR   OMA; YKTHATL; -.
DR   OrthoDB; 1283110at2759; -.
DR   SignaLink; P34450; -.
DR   PRO; PR:P34450; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00018833; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   SMART; SM00355; ZnF_C2H2; 5.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   4: Predicted;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..582
FT                   /note="Zinc finger transcription factor family protein 1"
FT                   /id="PRO_0000046897"
FT   ZN_FING         102..125
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         130..154
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         213..235
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   582 AA;  66806 MW;  1A5FD4A231348045 CRC64;
     MSEALETGDP SPPPPIVSEN GKTYYYLNSQ ESQAPNTPSP QEVPPKKMTN LFESGPLVYE
     DVAADIEAVT ERASRRHYEN KMVVKNSREM FDNVNILPDG RYYCCLCNRP YKTHATLTAH
     LRGYHLRNES SCDEPGCNFL SFTDQEKKRH RRTHDKKKKE RNSQESMVIH EKIQKAVRRL
     DYPGEDELRD HLNGSTEVQG TIRTMTKKGK IRYACLKCPH SVFNAYHAAR HVEMHNDFPK
     NCFYCGEIRK GTVDLQVHYM RVHKHEGIRT FKCSVCHLRF TTTILFRDHV ECENGCQNPE
     IRQDIYYGEL PEGTIVDDLT QDRLQNFRKR QEIWKTMGQM VEEHRTDVHE EIVGESSVQA
     GDTTVFDGSR AFIQTPFGLK TALEVKNTSR FCPRSGKRTS DDDLMITNKK RERLEMAPNL
     HFHQDIIHRL PTSTTTQRQN NAFQNEYLRP PVSYGYDPLI GRYPDFQLMS QSSLPSSSAS
     SSSYDPFATA VYQDSDRNPM QPNDQHICDM NNVGAYETAN FGLDNSSDLV VNEATIASNL
     MVNEVEDEVF EELNKLDFVM PADDGNDNDD DLEEVFNFGN VA