ID   ZUPT_CLOPE              Reviewed;         285 AA.
AC   Q8XMG8;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   27-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Zinc transporter ZupT;
GN   Name=zupT; OrderedLocusNames=CPE0721;
OS   Clostridium perfringens (strain 13 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=195102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=13 / Type A;
RX   PubMed=11792842; DOI=10.1073/pnas.022493799;
RA   Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T.,
RA   Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT   "Complete genome sequence of Clostridium perfringens, an anaerobic flesh-
RT   eater.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
CC   -!- FUNCTION: Mediates zinc uptake. May also transport other divalent
CC       cations (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT
CC       subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000016; BAB80427.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8XMG8; -.
DR   SMR; Q8XMG8; -.
DR   STRING; 195102.gene:10489983; -.
DR   EnsemblBacteria; BAB80427; BAB80427; BAB80427.
DR   KEGG; cpe:CPE0721; -.
DR   HOGENOM; CLU_015114_1_3_9; -.
DR   OMA; REYGEHH; -.
DR   Proteomes; UP000000818; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00548; ZupT; 1.
DR   InterPro; IPR003689; ZIP.
DR   InterPro; IPR023498; Zn_transptr_ZupT.
DR   Pfam; PF02535; Zip; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport; Zinc; Zinc transport.
FT   CHAIN           1..285
FT                   /note="Zinc transporter ZupT"
FT                   /id="PRO_0000207268"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        228..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        265..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   285 AA;  30630 MW;  145FD6552A3A142A CRC64;
     MKGGDNMNNV LMAFLLTLLA GLATGIGSCI AFFAKKTNKK FLCVSLGFSA GVMIYVSMIE
     MFQTAKESLV GVMGIKAGNW ITVISFFAGI AIIALIDKFV PEEENPHEVR SVEEVENEIE
     EYKGENKEGK ADIKDKTLMR TGIVTALAIA IHNFPEGLAT FVSALEGASL AIPITIAIAI
     HNIPEGISVS VPIFYATGDK KKAFLYSFLS GMSEPIGAII GYTLLRNIFN DITLGILLSA
     VAGIMVFISL DELLPTARKY GEHHLAIYGL IAGMVVMAVS LLLFI