ID   ZUPT_COREF              Reviewed;         268 AA.
AC   Q8FTK0;
DT   01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Zinc transporter ZupT {ECO:0000255|HAMAP-Rule:MF_00548};
GN   Name=zupT {ECO:0000255|HAMAP-Rule:MF_00548}; OrderedLocusNames=CE1566;
OS   Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189
OS   / NBRC 100395).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=196164;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395;
RX   PubMed=12840036; DOI=10.1101/gr.1285603;
RA   Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S.,
RA   Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.;
RT   "Comparative complete genome sequence analysis of the amino acid
RT   replacements responsible for the thermostability of Corynebacterium
RT   efficiens.";
RL   Genome Res. 13:1572-1579(2003).
CC   -!- FUNCTION: Mediates zinc uptake. May also transport other divalent
CC       cations. {ECO:0000255|HAMAP-Rule:MF_00548}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00548};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00548}.
CC   -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00548}.
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DR   EMBL; BA000035; BAC18376.1; -; Genomic_DNA.
DR   RefSeq; WP_011075511.1; NC_004369.1.
DR   AlphaFoldDB; Q8FTK0; -.
DR   SMR; Q8FTK0; -.
DR   STRING; 196164.23493406; -.
DR   EnsemblBacteria; BAC18376; BAC18376; BAC18376.
DR   KEGG; cef:CE1566; -.
DR   eggNOG; COG0428; Bacteria.
DR   HOGENOM; CLU_015114_1_3_11; -.
DR   OMA; MIFVVIE; -.
DR   OrthoDB; 1469769at2; -.
DR   Proteomes; UP000001409; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00548; ZupT; 1.
DR   InterPro; IPR003689; ZIP.
DR   InterPro; IPR023498; Zn_transptr_ZupT.
DR   Pfam; PF02535; Zip; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport; Zinc; Zinc transport.
FT   CHAIN           1..268
FT                   /note="Zinc transporter ZupT"
FT                   /id="PRO_0000207269"
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        37..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        74..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        126..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        153..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        211..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        248..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
SQ   SEQUENCE   268 AA;  27696 MW;  76E11825A0DB3E42 CRC64;
     MDWSNIIFAF SLTLFAGLAT GVGGVIAVAR KAPGERFLAG SLGFSVGVML FVSFVEILPK
     AVEELTGVWG ERGGNWAATG AFFAGIALIA VIDRLVPTAI NPHEPSTVGG AVEGYERRSR
     MMRAGVLTAI AISIHNFPEG FATFVAGLTD PRIAIPVAVA IAIHNIPEGI AVAVPIREAT
     GSRGKALKWA TLSGLAEPAG AVVGFILLMP FLGPEAMGLS FAAVAGIMVF ISLDELLPTA
     ISSGRHHTAI YGLVGGMAVM AVSLLLFI