ID   ZUPT_OCEIH              Reviewed;         268 AA.
AC   Q8ENQ1;
DT   03-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Zinc transporter ZupT {ECO:0000255|HAMAP-Rule:MF_00548};
GN   Name=zupT {ECO:0000255|HAMAP-Rule:MF_00548}; OrderedLocusNames=OB2427;
OS   Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC
OS   3954 / HTE831).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX   NCBI_TaxID=221109;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831;
RX   PubMed=12235376; DOI=10.1093/nar/gkf526;
RA   Takami H., Takaki Y., Uchiyama I.;
RT   "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge
RT   and its unexpected adaptive capabilities to extreme environments.";
RL   Nucleic Acids Res. 30:3927-3935(2002).
CC   -!- FUNCTION: Mediates zinc uptake. May also transport other divalent
CC       cations. {ECO:0000255|HAMAP-Rule:MF_00548}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00548};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00548}.
CC   -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00548}.
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DR   EMBL; BA000028; BAC14383.1; -; Genomic_DNA.
DR   RefSeq; WP_011066818.1; NC_004193.1.
DR   AlphaFoldDB; Q8ENQ1; -.
DR   SMR; Q8ENQ1; -.
DR   STRING; 221109.22778113; -.
DR   EnsemblBacteria; BAC14383; BAC14383; BAC14383.
DR   KEGG; oih:OB2427; -.
DR   eggNOG; COG0428; Bacteria.
DR   HOGENOM; CLU_015114_1_3_9; -.
DR   OMA; REYGEHH; -.
DR   OrthoDB; 1469769at2; -.
DR   PhylomeDB; Q8ENQ1; -.
DR   Proteomes; UP000000822; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00548; ZupT; 1.
DR   InterPro; IPR003689; ZIP.
DR   InterPro; IPR023498; Zn_transptr_ZupT.
DR   Pfam; PF02535; Zip; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport; Zinc; Zinc transport.
FT   CHAIN           1..268
FT                   /note="Zinc transporter ZupT"
FT                   /id="PRO_0000207276"
FT   TRANSMEM        4..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        35..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        72..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        126..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        155..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        189..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        215..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
FT   TRANSMEM        250..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00548"
SQ   SEQUENCE   268 AA;  29074 MW;  393A3C339277E0C9 CRC64;
     MDNMLLAFLL TLFAGLATGV GSLIAFMAKT TNTKFLSFAL GLSAGVMIYV SMVDIFFKAK
     DALTAYLGDT QGYWLTVIAF FGGMLLIGFI DRFIPKYTNP HEVKKVEDMK KPHQPLRDPD
     LMKMGLFTAL ALAIHNFPEG IATFVSTLHD PSIGLAIAIA VAIHNIPEGI AVSVPIYYAT
     GDRKKAFKYS FLSGLAEPLG AIVAILILMP FLNDLMFGII FAMVAGIMVF ISLDELLPAA
     RKYDEAHMSM YGVISGMALM AVSLLLLA