ZWIP3_ARATH
ID ZWIP3_ARATH Reviewed; 337 AA.
AC Q9SGD1;
DT 26-NOV-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 161.
DE RecName: Full=Zinc finger protein WIP3;
DE AltName: Full=WIP-domain protein 3 {ECO:0000303|PubMed:11782451};
DE Short=AtWIP3 {ECO:0000303|PubMed:11782451};
GN Name=WIP3 {ECO:0000303|PubMed:11782451};
GN OrderedLocusNames=At1g08290 {ECO:0000312|Araport:AT1G08290};
GN ORFNames=T23G18.15 {ECO:0000312|EMBL:AAF18247.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11782451; DOI=10.1101/gad.212702;
RA Sagasser M., Lu G.-H., Hahlbrock K., Weisshaar B.;
RT "A. thaliana TRANSPARENT TESTA 1 is involved in seed coat development and
RT defines the WIP subfamily of plant zinc finger proteins.";
RL Genes Dev. 16:138-149(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP SUBCELLULAR LOCATION, AND ZINC-FINGER.
RX PubMed=20541552; DOI=10.1016/j.febslet.2010.06.007;
RA Appelhagen I., Huep G., Lu G.H., Strompen G., Weisshaar B., Sagasser M.;
RT "Weird fingers: functional analysis of WIP domain proteins.";
RL FEBS Lett. 584:3116-3122(2010).
CC -!- FUNCTION: Probable transcriptional regulator.
CC {ECO:0000305|PubMed:20541552}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20541552}.
CC -!- SIMILARITY: Belongs to the WIP C2H2-type zinc-finger protein family.
CC {ECO:0000305}.
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DR EMBL; AF254448; AAL55723.1; -; mRNA.
DR EMBL; AC011438; AAF18247.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE28270.1; -; Genomic_DNA.
DR EMBL; AK118851; BAC43439.1; -; mRNA.
DR EMBL; AY090918; AAM13913.1; -; mRNA.
DR RefSeq; NP_172306.1; NM_100702.4.
DR AlphaFoldDB; Q9SGD1; -.
DR BioGRID; 22590; 8.
DR IntAct; Q9SGD1; 3.
DR STRING; 3702.AT1G08290.1; -.
DR PaxDb; Q9SGD1; -.
DR PRIDE; Q9SGD1; -.
DR ProteomicsDB; 242951; -.
DR EnsemblPlants; AT1G08290.1; AT1G08290.1; AT1G08290.
DR GeneID; 837349; -.
DR Gramene; AT1G08290.1; AT1G08290.1; AT1G08290.
DR KEGG; ath:AT1G08290; -.
DR Araport; AT1G08290; -.
DR TAIR; locus:2200003; AT1G08290.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_052255_0_0_1; -.
DR InParanoid; Q9SGD1; -.
DR OMA; DHDEKEC; -.
DR OrthoDB; 1318335at2759; -.
DR PhylomeDB; Q9SGD1; -.
DR PRO; PR:Q9SGD1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SGD1; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IBA:GO_Central.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR043584; WIP1/2/3/4/5/6.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45878; PTHR45878; 1.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF57667; SSF57667; 2.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 2: Evidence at transcript level;
KW Metal-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..337
FT /note="Zinc finger protein WIP3"
FT /id="PRO_0000431317"
FT ZN_FING 180..202
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 228..260
FT /note="C2H2-type 2; atypical"
FT /evidence="ECO:0000303|PubMed:20541552"
FT ZN_FING 265..287
FT /note="C2H2-type 3; atypical"
FT /evidence="ECO:0000303|PubMed:20541552"
FT ZN_FING 291..316
FT /note="C2H2-type 4; atypical"
FT /evidence="ECO:0000303|PubMed:20541552"
FT MOTIF 257..260
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250|UniProtKB:Q8VWG3"
FT MOTIF 300..303
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250|UniProtKB:Q8VWG3"
SQ SEQUENCE 337 AA; 38596 MW; BEA02344F5C3ED05 CRC64;
MNSYETKGLS FESPSFIEWL KPQSSTTSSK SVLYRGKTRD AISRSNHHQS QMNMLERSLF
LYQPQEPLNT SIQCLPLLNK LMENNSQASD IKEENKDDVV TLQIGFPKYH RGSSEDGSDI
TFDHQKKPIK REIIEDGVVM MKKRRKMKFD EEIIDSDVEV CGKRFWIPSP AQIHVGPMQF
ACSICSKTFN RYNNMQMHMW GHGSEFRKGA DSLKGTIQPA AILRLPCYCC AEGCKNNINH
PRSKPLKDFR TLQTHYKRKH GSKPFSCGKC GKALAVKGDW RTHEKNCGKL WYCTCGSDFK
HKRSLKDHIR SFGSGHSPHP SLLFDGFEED TECVTTE