ZWIP5_ARATH
ID ZWIP5_ARATH Reviewed; 337 AA.
AC Q8W031; Q9SYC5;
DT 26-NOV-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Zinc finger protein WIP5;
DE AltName: Full=WIP-domain protein 5 {ECO:0000303|PubMed:11782451};
DE Short=AtWIP5 {ECO:0000303|PubMed:11782451};
GN Name=WIP5 {ECO:0000303|PubMed:11782451};
GN OrderedLocusNames=At1g51220 {ECO:0000312|Araport:AT1G51220};
GN ORFNames=F11M15.9 {ECO:0000312|EMBL:AAD30636.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11782451; DOI=10.1101/gad.212702;
RA Sagasser M., Lu G.-H., Hahlbrock K., Weisshaar B.;
RT "A. thaliana TRANSPARENT TESTA 1 is involved in seed coat development and
RT defines the WIP subfamily of plant zinc finger proteins.";
RL Genes Dev. 16:138-149(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP SUBCELLULAR LOCATION, AND ZINC-FINGER.
RX PubMed=20541552; DOI=10.1016/j.febslet.2010.06.007;
RA Appelhagen I., Huep G., Lu G.H., Strompen G., Weisshaar B., Sagasser M.;
RT "Weird fingers: functional analysis of WIP domain proteins.";
RL FEBS Lett. 584:3116-3122(2010).
CC -!- FUNCTION: Probable transcriptional regulator.
CC {ECO:0000305|PubMed:20541552}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20541552}.
CC -!- SIMILARITY: Belongs to the WIP C2H2-type zinc-finger protein family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD30636.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ311810; CAC86167.1; -; mRNA.
DR EMBL; AC006085; AAD30636.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE32638.1; -; Genomic_DNA.
DR PIR; A96550; A96550.
DR RefSeq; NP_175533.1; NM_104000.2.
DR AlphaFoldDB; Q8W031; -.
DR STRING; 3702.AT1G51220.1; -.
DR PaxDb; Q8W031; -.
DR PRIDE; Q8W031; -.
DR EnsemblPlants; AT1G51220.1; AT1G51220.1; AT1G51220.
DR GeneID; 841545; -.
DR Gramene; AT1G51220.1; AT1G51220.1; AT1G51220.
DR KEGG; ath:AT1G51220; -.
DR Araport; AT1G51220; -.
DR TAIR; locus:2008281; AT1G51220.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_052255_0_1_1; -.
DR InParanoid; Q8W031; -.
DR OMA; DNESSHC; -.
DR OrthoDB; 1318335at2759; -.
DR PhylomeDB; Q8W031; -.
DR PRO; PR:Q8W031; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8W031; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IBA:GO_Central.
DR GO; GO:0080022; P:primary root development; IGI:TAIR.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR043584; WIP1/2/3/4/5/6.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45878; PTHR45878; 1.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 2: Evidence at transcript level;
KW Metal-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..337
FT /note="Zinc finger protein WIP5"
FT /id="PRO_0000431319"
FT ZN_FING 178..200
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 225..257
FT /note="C2H2-type 2; atypical"
FT /evidence="ECO:0000303|PubMed:20541552"
FT ZN_FING 262..284
FT /note="C2H2-type 3; atypical"
FT /evidence="ECO:0000303|PubMed:20541552"
FT ZN_FING 288..313
FT /note="C2H2-type 4; atypical"
FT /evidence="ECO:0000303|PubMed:20541552"
FT MOTIF 254..257
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250|UniProtKB:Q8VWG3"
FT MOTIF 297..300
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250|UniProtKB:Q8VWG3"
SQ SEQUENCE 337 AA; 38238 MW; 40C0210F8D9E1B0A CRC64;
MSNPACSNLF NNGCDHNSFN YSTSLSYIYN SHGSYYYSNT TNPNYINHTH TTSTSPNSPP
LREALPLLSL SPIRHQEQQD QHYFMDTHQI SSSNFLDDPL VTVDLHLGLP NYGVGESIRS
NIAPDATTDE QDQDHDRGVE VTVESHLDDD DDHHGDLHRG HHYWIPTPSQ ILIGPTQFTC
PLCFKTFNRY NNMQMHMWGH GSQYRKGPES LRGTQPTGML RLPCFCCAPG CKNNIDHPRA
KPLKDFRTLQ THYKRKHGSK PFACRMCGKA FAVKGDWRTH EKNCGKLWYC SCGSDFKHKR
SLKDHVKAFG NGHVPCGIDS FGGDHEDYYD AASDIEQ
