ID   ZYG1_DICMU              Reviewed;         268 AA.
AC   Q76N59;
DT   15-DEC-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 25.
DE   RecName: Full=Zygote formation protein zyg1;
GN   Name=zyg1;
OS   Dictyostelium mucoroides (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=31287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RX   PubMed=12952084; DOI=10.1023/a:1024448316675;
RA   Amagai A.;
RT   "Involvement of a novel gene, zyg1, in zygote formation of Dictyostelium
RT   mucoroides.";
RL   J. Muscle Res. Cell Motil. 23:867-874(2002).
RN   [2]
RP   INDUCTION, AND DEVELOPMENTAL STAGE.
RX   PubMed=17499244; DOI=10.1016/j.yexcr.2007.04.012;
RA   Amagai A., Soramoto S., Saito S., Maeda Y.;
RT   "Ethylene induces zygote formation through an enhanced expression of zyg1
RT   in Dictyostelium mucoroides.";
RL   Exp. Cell Res. 313:2493-2503(2007).
CC   -!- FUNCTION: Plays an essential role in zygote formation by inducing
CC       sexual cell fusion. Overexpressing cells eventually formed many loose
CC       mounds, in which giant multinucleate cells were surrounded by normal-
CC       sized cells. {ECO:0000269|PubMed:12952084}.
CC   -!- DEVELOPMENTAL STAGE: Expression lasts until zygotes are formed.
CC       {ECO:0000269|PubMed:17499244}.
CC   -!- INDUCTION: Expression augmented in cells that overproduce ethylene but
CC       significantly suppressed in cells that have lower ethylene production.
CC       {ECO:0000269|PubMed:17499244}.
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DR   EMBL; AB006956; BAC87708.1; -; mRNA.
DR   AlphaFoldDB; Q76N59; -.
DR   SMR; Q76N59; -.
PE   2: Evidence at transcript level;
KW   Developmental protein.
FT   CHAIN           1..268
FT                   /note="Zygote formation protein zyg1"
FT                   /id="PRO_0000390406"
SQ   SEQUENCE   268 AA;  29379 MW;  059D15BE4561EE78 CRC64;
     MEIDSKITNF EDAGTINLNL HNFVSEKFAN KPKVLNVASL ASNSVDEAGD SEQKVSFRIN
     QTGNIFYSTT TPELTLESKK LFNSVTVLFA AMTKALGEKG LNLFNYEAVA SLIQKSGYFV
     EVQKFQKNLS IKSGSLSIDT QIIQQLIPGL TSGASLDIAK GVLGALNGEF SASSSDEKVK
     IAHLLFICEE LFGAPSVTVR LFYATKETHK TLTSSPCHKS SSVSFELNQE ASTFLFVSPD
     TIAEFSQKFE TQPEEYKNLI EKLKGYLP