CCB11_ARATH
ID CCB11_ARATH Reviewed; 428 AA.
AC P30183; Q08A73; Q42081;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2000, sequence version 2.
DT 03-AUG-2022, entry version 155.
DE RecName: Full=Cyclin-B1-1;
DE AltName: Full=Cyc1-At;
DE AltName: Full=G2/mitotic-specific cyclin-B1-1;
DE Short=CycB1;1;
GN Name=CYCB1-1; Synonyms=CYC1; OrderedLocusNames=At4g37490;
GN ORFNames=F6G17.140;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND
RP DEVELOPMENTAL STAGE.
RC STRAIN=cv. C24;
RX PubMed=1373494; DOI=10.1073/pnas.89.8.3295;
RA Hemerly A.S., Bergounioux C., van Montagu M., Inze D., Ferreira P.C.G.;
RT "Genes regulating the plant cell cycle: isolation of a mitotic-like cyclin
RT from Arabidopsis thaliana.";
RL Proc. Natl. Acad. Sci. U.S.A. 89:3295-3299(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 6-94.
RC STRAIN=cv. Columbia;
RX PubMed=8580968; DOI=10.1046/j.1365-313x.1996.09010101.x;
RA Cooke R., Raynal M., Laudie M., Grellet F., Delseny M., Morris P.-C.,
RA Guerrier D., Giraudat J., Quigley F., Clabault G., Li Y.-F., Mache R.,
RA Krivitzky M., Gy I.J.-J., Kreis M., Lecharny A., Parmentier Y., Marbach J.,
RA Fleck J., Clement B., Philipps G., Herve C., Bardet C., Tremousaygue D.,
RA Lescure B., Lacomme C., Roby D., Jourjon M.-F., Chabrier P.,
RA Charpenteau J.-L., Desprez T., Amselem J., Chiapello H., Hoefte H.;
RT "Further progress towards a catalogue of all Arabidopsis genes: analysis of
RT a set of 5000 non-redundant ESTs.";
RL Plant J. 9:101-124(1996).
RN [6]
RP TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND INDUCTION.
RX PubMed=7866022; DOI=10.2307/3869906;
RA Ferreira P.C.G., Hemerly A.S., de Almeida Engler J., van Montagu M.,
RA Engler G., Inze D.;
RT "Developmental expression of the arabidopsis cyclin gene cyc1At.";
RL Plant Cell 6:1763-1774(1994).
RN [7]
RP INDUCTION.
RX PubMed=9011085; DOI=10.1046/j.1365-313x.1996.10061037.x;
RA Niebel A., de Almeida Engler J., Hemerly A.S., Ferreira P.C.G., Inze D.,
RA van Montagu M., Gheysen G.;
RT "Induction of cdc2a and cyc1At expression in Arabidopsis thaliana during
RT early phases of nematode-induced feeding cell formation.";
RL Plant J. 10:1037-1043(1996).
RN [8]
RP INDUCTION.
RX PubMed=11089675; DOI=10.1007/s004250000334;
RA Burssens S., Himanen K., van de Cotte B., Beeckman T., van Montagu M.,
RA Inze D., Verbruggen N.;
RT "Expression of cell cycle regulatory genes and morphological alterations in
RT response to salt stress in Arabidopsis thaliana.";
RL Planta 211:632-640(2000).
RN [9]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15208425; DOI=10.1104/pp.104.040436;
RA Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA Ma H.;
RT "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT phylogenetic analysis of plant cyclin-like proteins.";
RL Plant Physiol. 135:1084-1099(2004).
RN [10]
RP DEVELOPMENTAL STAGE, AND INTERACTION WITH FZR1; FZR2 AND FZR3.
RX PubMed=15970679;
RA Fueloep K., Tarayre S., Kelemen Z., Horvath G., Kevei Z., Nikovics K.,
RA Bako L., Brown S., Kondorosi A., Kondorosi E.;
RT "Arabidopsis anaphase-promoting complexes: multiple activators and wide
RT range of substrates might keep APC perpetually busy.";
RL Cell Cycle 4:1084-1092(2005).
CC -!- SUBUNIT: Interacts with FZR2/CCS52A1, FZR1/CCS52A2 and FZR3/CCS52B.
CC {ECO:0000269|PubMed:15970679}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:1373494}.
CC -!- TISSUE SPECIFICITY: Expressed in root tip, lateral root apex, shoot
CC apex, leaf primordia, axillary buds, stamen and petal primordia, ovules
CC and developing embryo. {ECO:0000269|PubMed:1373494,
CC ECO:0000269|PubMed:7866022}.
CC -!- DEVELOPMENTAL STAGE: Expressed early in the G2 phase, reaches a peak at
CC mitosis and then decreases. Expressed in the developing embryo up to
CC the late-heart and early-torpedo stages. {ECO:0000269|PubMed:1373494,
CC ECO:0000269|PubMed:15970679, ECO:0000269|PubMed:7866022}.
CC -!- INDUCTION: By auxin and nematode infection in roots. Down-regulated by
CC salt stress in root meristem and shoot apex.
CC {ECO:0000269|PubMed:11089675, ECO:0000269|PubMed:7866022,
CC ECO:0000269|PubMed:9011085}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000305}.
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DR EMBL; M80190; AAA32781.1; -; mRNA.
DR EMBL; X62279; CAA44169.1; -; mRNA.
DR EMBL; AL035601; CAB38216.1; -; Genomic_DNA.
DR EMBL; AL161591; CAB80414.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE86801.1; -; Genomic_DNA.
DR EMBL; BT029006; ABI93915.1; -; mRNA.
DR EMBL; Z26397; CAA81236.1; -; mRNA.
DR PIR; T04743; T04743.
DR RefSeq; NP_195465.1; NM_119913.3.
DR AlphaFoldDB; P30183; -.
DR SMR; P30183; -.
DR BioGRID; 15185; 9.
DR IntAct; P30183; 4.
DR STRING; 3702.AT4G37490.1; -.
DR PaxDb; P30183; -.
DR PRIDE; P30183; -.
DR ProteomicsDB; 223961; -.
DR EnsemblPlants; AT4G37490.1; AT4G37490.1; AT4G37490.
DR GeneID; 829904; -.
DR Gramene; AT4G37490.1; AT4G37490.1; AT4G37490.
DR KEGG; ath:AT4G37490; -.
DR Araport; AT4G37490; -.
DR TAIR; locus:2126377; AT4G37490.
DR eggNOG; KOG0653; Eukaryota.
DR HOGENOM; CLU_020695_0_3_1; -.
DR InParanoid; P30183; -.
DR OMA; KMENMVH; -.
DR OrthoDB; 993640at2759; -.
DR PhylomeDB; P30183; -.
DR PRO; PR:P30183; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; P30183; baseline and differential.
DR Genevisible; P30183; AT.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR GO; GO:0001558; P:regulation of cell growth; IMP:TAIR.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:0010332; P:response to gamma radiation; IEP:TAIR.
DR CDD; cd00043; CYCLIN; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177; PTHR10177; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; SSF47954; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Cyclin; Nucleus; Reference proteome.
FT CHAIN 1..428
FT /note="Cyclin-B1-1"
FT /id="PRO_0000080391"
FT CONFLICT 91
FT /note="K -> N (in Ref. 1; AAA32781/CAA44169)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 428 AA; 48460 MW; 83334927768D8857 CRC64;
MMTSRSIVPQ QSTDDVVVVD GKNVAKGRNR QVLGDIGNVV RGNYPKNNEP EKINHRPRTR
SQNPTLLVED NLKKPVVKRN AVPKPKKVAG KPKVVDVIEI SSDSDEELGL VAAREKKATK
KKATTYTSVL TARSKAACGL EKKQKEKIVD IDSADVENDL AAVEYVEDIY SFYKSVESEW
RPRDYMASQP DINEKMRLIL VEWLIDVHVR FELNPETFYL TVNILDRFLS VKPVPRKELQ
LVGLSALLMS AKYEEIWPPQ VEDLVDIADH AYSHKQILVM EKTILSTLEW YLTVPTHYVF
LARFIKASIA DEKMENMVHY LAELGVMHYD TMIMFSPSMV AASAIYAARS SLRQVPIWTS
TLKHHTGYSE TQLMDCAKLL AYQQWKQQEE GSESSTKGAL RKKYSKDERF AVALIPPAKA
LLTGTESA
