CCB13_ARATH
ID CCB13_ARATH Reviewed; 414 AA.
AC Q39069; Q84MB0; Q9CAX5;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 2.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Cyclin-B1-3;
DE AltName: Full=Cyc2-At;
DE AltName: Full=G2/mitotic-specific cyclin-B1-3;
DE Short=CycB1;3;
GN Name=CYCB1-3; Synonyms=CYC2; OrderedLocusNames=At3g11520;
GN ORFNames=F24K9.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 190-253.
RC TISSUE=Flower meristem;
RX PubMed=8193159; DOI=10.1016/0167-4781(94)90112-0;
RA Day I.S., Reddy A.S.;
RT "Cloning of a family of cyclins from Arabidopsis thaliana.";
RL Biochim. Biophys. Acta 1218:115-118(1994).
RN [6]
RP DEVELOPMENTAL STAGE.
RX PubMed=8938409; DOI=10.1104/pp.112.3.1023;
RA Fuerst R.A.U., Soni R., Murray J.A.H., Lindsey K.;
RT "Modulation of cyclin transcript levels in cultured cells of Arabidopsis
RT thaliana.";
RL Plant Physiol. 112:1023-1033(1996).
RN [7]
RP TISSUE SPECIFICITY.
RX PubMed=9484485; DOI=10.1023/a:1005959311462;
RA Day I.S., Reddy A.S.;
RT "Isolation and characterization of two cyclin-like cDNAs from
RT Arabidopsis.";
RL Plant Mol. Biol. 36:451-461(1998).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15208425; DOI=10.1104/pp.104.040436;
RA Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA Ma H.;
RT "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT phylogenetic analysis of plant cyclin-like proteins.";
RL Plant Physiol. 135:1084-1099(2004).
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems and flowers.
CC {ECO:0000269|PubMed:9484485}.
CC -!- DEVELOPMENTAL STAGE: Starts to be expressed at the end of S phase,
CC reaches a peak at mitosis and then decreases.
CC {ECO:0000269|PubMed:8938409}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG51435.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC008153; AAG51435.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE75057.1; -; Genomic_DNA.
DR EMBL; BT006437; AAP21245.1; -; mRNA.
DR EMBL; AK227951; BAE99919.1; -; mRNA.
DR EMBL; L27224; AAA19879.1; -; mRNA.
DR PIR; S45294; S45294.
DR RefSeq; NP_187759.2; NM_111985.5.
DR AlphaFoldDB; Q39069; -.
DR SMR; Q39069; -.
DR BioGRID; 5659; 12.
DR IntAct; Q39069; 10.
DR STRING; 3702.AT3G11520.1; -.
DR PaxDb; Q39069; -.
DR PRIDE; Q39069; -.
DR ProteomicsDB; 239100; -.
DR DNASU; 820325; -.
DR EnsemblPlants; AT3G11520.1; AT3G11520.1; AT3G11520.
DR GeneID; 820325; -.
DR Gramene; AT3G11520.1; AT3G11520.1; AT3G11520.
DR KEGG; ath:AT3G11520; -.
DR Araport; AT3G11520; -.
DR TAIR; locus:2080717; AT3G11520.
DR eggNOG; KOG0653; Eukaryota.
DR HOGENOM; CLU_020695_0_3_1; -.
DR InParanoid; Q39069; -.
DR OMA; YNEQQLM; -.
DR OrthoDB; 993640at2759; -.
DR PhylomeDB; Q39069; -.
DR PRO; PR:Q39069; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q39069; baseline and differential.
DR Genevisible; Q39069; AT.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR CDD; cd00043; CYCLIN; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177; PTHR10177; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; SSF47954; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Cyclin; Reference proteome.
FT CHAIN 1..414
FT /note="Cyclin-B1-3"
FT /id="PRO_0000287005"
SQ SEQUENCE 414 AA; 46267 MW; 12217A03C2055FA6 CRC64;
MATGPVVHPQ PVRGDPIDLK NAAAKNRRAL GDIGNVDSLI GVEGGKLNRP ITRNFRAQLL
ENAQVAAAAN KKAPILDGVT KKQEVVRAVQ KKARGDKREP SKPIEVIVIS PDTNEVAKAK
ENKKKVTYSS VLDARSKAAS KTLDIDYVDK ENDLAAVEYV EDMYIFYKEV VNESKPQMYM
HTQPEIDEKM RSILIDWLVE VHVKFDLSPE TLYLTVNIID RFLSLKTVPR RELQLVGVSA
LLIASKYEEI WPPQVNDLVY VTDNSYNSRQ ILVMEKTILG NLEWYLTVPT QYVFLVRFIK
ASGSDQKLEN LVHFLAELGL MHHDSLMFCP SMLAASAVYT ARCCLNKTPT WTDTLKFHTG
YSESQLMDCS KLLAFIHSKA GESKLRGVLK KYSKLGRGAV ALISPAKSLM SSAP
