CCB15_ARATH
ID CCB15_ARATH Reviewed; 491 AA.
AC Q39072; F4HUZ7; Q9LNK6;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-NOV-2011, sequence version 3.
DT 25-MAY-2022, entry version 121.
DE RecName: Full=Cyclin-B1-5;
DE AltName: Full=Cyc3-At;
DE AltName: Full=G2/mitotic-specific cyclin-B1-5;
DE Short=CycB1;5;
GN Name=CYCB1-5; Synonyms=CYC3; OrderedLocusNames=At1g34460;
GN ORFNames=F12K21.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 303-348.
RC TISSUE=Flower meristem;
RX PubMed=8193159; DOI=10.1016/0167-4781(94)90112-0;
RA Day I.S., Reddy A.S.;
RT "Cloning of a family of cyclins from Arabidopsis thaliana.";
RL Biochim. Biophys. Acta 1218:115-118(1994).
RN [4]
RP DEVELOPMENTAL STAGE.
RX PubMed=8938409; DOI=10.1104/pp.112.3.1023;
RA Fuerst R.A.U., Soni R., Murray J.A.H., Lindsey K.;
RT "Modulation of cyclin transcript levels in cultured cells of Arabidopsis
RT thaliana.";
RL Plant Physiol. 112:1023-1033(1996).
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=9484485; DOI=10.1023/a:1005959311462;
RA Day I.S., Reddy A.S.;
RT "Isolation and characterization of two cyclin-like cDNAs from
RT Arabidopsis.";
RL Plant Mol. Biol. 36:451-461(1998).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15208425; DOI=10.1104/pp.104.040436;
RA Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA Ma H.;
RT "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT phylogenetic analysis of plant cyclin-like proteins.";
RL Plant Physiol. 135:1084-1099(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q39072-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems and flowers.
CC {ECO:0000269|PubMed:9484485}.
CC -!- DEVELOPMENTAL STAGE: Starts to be expressed during the S phase, reaches
CC a peak at mitosis and then decreases. {ECO:0000269|PubMed:8938409}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA19880.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
CC Sequence=AAF79265.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC023279; AAF79265.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31715.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM57698.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM57702.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM57704.1; -; Genomic_DNA.
DR EMBL; L27225; AAA19880.1; ALT_SEQ; mRNA.
DR PIR; G86468; G86468.
DR PIR; S45295; S45295.
DR RefSeq; NP_001319145.1; NM_001333104.1. [Q39072-1]
DR RefSeq; NP_001320186.1; NM_001333106.1. [Q39072-1]
DR RefSeq; NP_001320190.1; NM_001333109.1. [Q39072-1]
DR RefSeq; NP_564446.3; NM_103168.4. [Q39072-1]
DR AlphaFoldDB; Q39072; -.
DR SMR; Q39072; -.
DR STRING; 3702.AT1G34460.1; -.
DR PaxDb; Q39072; -.
DR PRIDE; Q39072; -.
DR EnsemblPlants; AT1G34460.1; AT1G34460.1; AT1G34460. [Q39072-1]
DR EnsemblPlants; AT1G34460.3; AT1G34460.3; AT1G34460. [Q39072-1]
DR EnsemblPlants; AT1G34460.6; AT1G34460.6; AT1G34460. [Q39072-1]
DR EnsemblPlants; AT1G34460.8; AT1G34460.8; AT1G34460. [Q39072-1]
DR GeneID; 840348; -.
DR Gramene; AT1G34460.1; AT1G34460.1; AT1G34460. [Q39072-1]
DR Gramene; AT1G34460.3; AT1G34460.3; AT1G34460. [Q39072-1]
DR Gramene; AT1G34460.6; AT1G34460.6; AT1G34460. [Q39072-1]
DR Gramene; AT1G34460.8; AT1G34460.8; AT1G34460. [Q39072-1]
DR KEGG; ath:AT1G34460; -.
DR Araport; AT1G34460; -.
DR TAIR; locus:2806635; AT1G34460.
DR eggNOG; KOG0653; Eukaryota.
DR eggNOG; KOG1340; Eukaryota.
DR HOGENOM; CLU_565458_0_0_1; -.
DR InParanoid; Q39072; -.
DR PRO; PR:Q39072; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q39072; baseline and differential.
DR Genevisible; Q39072; AT.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR CDD; cd00043; CYCLIN; 1.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177; PTHR10177; 2.
DR Pfam; PF00134; Cyclin_N; 1.
DR SUPFAM; SSF47954; SSF47954; 1.
DR PROSITE; PS00292; CYCLINS; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Cell cycle; Cell division; Cyclin;
KW Reference proteome.
FT CHAIN 1..491
FT /note="Cyclin-B1-5"
FT /id="PRO_0000287007"
FT DOMAIN 275..347
FT /note="Cyclin N-terminal"
SQ SEQUENCE 491 AA; 55430 MW; 98A5591A11694837 CRC64;
MAHYINIYGK RLFDIGLYLK TSVDLILQQQ HVLMSQQKFT DISLCHREAP NPKLDLPDDN
RLSPLTELED IGQQSKTLGT AIHRKISEQK RVIESGSVAS IVEHKRTNLS AIMATRANIP
EQVRGAPLVD GLKIQNKNGA VKNRRALGDI GNLVSVPGVQ GGKAQPPINR PITLSFRAQL
LANAQLERKP INGDNKVPAL GPKSQPLAAR NPEAQRAVQK KNLVVKQQTK PVEVIETKRN
AQSKAACGIV NKPKILDIDE SDKDNHVAAV EYVDDMYSFY KEVEKESQPK MYMHIQTEMN
EKMRAILIDW LLEVHIKFEL NLETLYLTVN IIDRFLYVKA VPKRELQVND LVYVTDNAYS
SRQILVMKKA ILGNLEWYLT IPTQYVFLFC FIKASISDPE VLHVQKKNLQ ASKTKSFSIQ
VLSFSSHKSI VKSDQFCKKF NLCQEVTALA SEFHLGNCEA WRETVTKLKD PETKCLKVVF
EYTASDACGY G
