CCB1_ARATH
ID CCB1_ARATH Reviewed; 267 AA.
AC Q9LSE4; Q38964;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Protein COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB1, chloroplastic {ECO:0000305};
DE Flags: Precursor;
GN Name=CCB1 {ECO:0000303|PubMed:18593701};
GN OrderedLocusNames=At3g26710 {ECO:0000312|Araport:AT3G26710};
GN ORFNames=MLJ15.10 {ECO:0000312|EMBL:BAB01734.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=8932388; DOI=10.1093/nar/24.21.4313;
RA Quigley F., Dao P., Cottet A., Mache R.;
RT "Sequence analysis of an 81 kb contig from Arabidopsis thaliana chromosome
RT III.";
RL Nucleic Acids Res. 24:4313-4318(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP FUNCTION, SUBCELLULAR LOCATION, TOPOLOGY, AND DISRUPTION PHENOTYPE.
RX PubMed=18593701; DOI=10.1074/jbc.m803869200;
RA Lezhneva L., Kuras R., Ephritikhine G., de Vitry C.;
RT "A novel pathway of cytochrome c biogenesis is involved in the assembly of
RT the cytochrome b6f complex in arabidopsis chloroplasts.";
RL J. Biol. Chem. 283:24608-24616(2008).
CC -!- FUNCTION: Required for the biogenesis and accumulation of native
CC cytochrome b6 in the thylakoid membrane. Controls the conversion of
CC apocytochrome b6 to holocytochrome b6. Required for covalent binding of
CC the c-type heme to cytochrome b6. {ECO:0000269|PubMed:18593701}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000305|PubMed:18593701}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- DISRUPTION PHENOTYPE: Seedling lethal when grown on soil. On agar
CC plates supplied with sucrose, seedlings grow very slowly with a
CC chlorotic phenotype. Deficiency in the accumulation of the subunits of
CC the cytochrome b6f complex and lack of covalent heme binding to
CC cytochrome b6. {ECO:0000269|PubMed:18593701}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA66820.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; X98130; CAA66820.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AB026648; BAB01734.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77202.1; -; Genomic_DNA.
DR EMBL; AY140025; AAM98166.1; -; mRNA.
DR EMBL; BT006294; AAP13402.1; -; mRNA.
DR EMBL; AK227251; BAE99286.1; -; mRNA.
DR EMBL; AY087129; AAM64687.1; -; mRNA.
DR RefSeq; NP_566797.1; NM_113582.5.
DR AlphaFoldDB; Q9LSE4; -.
DR STRING; 3702.AT3G26710.1; -.
DR PaxDb; Q9LSE4; -.
DR PRIDE; Q9LSE4; -.
DR ProteomicsDB; 223873; -.
DR EnsemblPlants; AT3G26710.1; AT3G26710.1; AT3G26710.
DR GeneID; 822283; -.
DR Gramene; AT3G26710.1; AT3G26710.1; AT3G26710.
DR KEGG; ath:AT3G26710; -.
DR Araport; AT3G26710; -.
DR TAIR; locus:2090807; AT3G26710.
DR eggNOG; ENOG502QR1Q; Eukaryota.
DR HOGENOM; CLU_067692_1_0_1; -.
DR InParanoid; Q9LSE4; -.
DR OMA; WFWLTIL; -.
DR OrthoDB; 1151953at2759; -.
DR PhylomeDB; Q9LSE4; -.
DR PRO; PR:Q9LSE4; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LSE4; baseline and differential.
DR Genevisible; Q9LSE4; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0010190; P:cytochrome b6f complex assembly; IMP:TAIR.
DR InterPro; IPR021919; CCB1.
DR PANTHER; PTHR35302; PTHR35302; 1.
DR Pfam; PF12046; CCB1; 1.
PE 1: Evidence at protein level;
KW Chloroplast; Membrane; Plastid; Reference proteome; Thylakoid;
KW Transit peptide; Transmembrane; Transmembrane helix.
FT TRANSIT 1..44
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 45..267
FT /note="Protein COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B
FT CCB1, chloroplastic"
FT /evidence="ECO:0000255"
FT /id="PRO_0000433262"
FT TOPO_DOM 45..84
FT /note="Lumenal"
FT /evidence="ECO:0000305|PubMed:18593701"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 106..164
FT /note="Stromal"
FT /evidence="ECO:0000305|PubMed:18593701"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 186
FT /note="Lumenal"
FT /evidence="ECO:0000305|PubMed:18593701"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 208..267
FT /note="Stromal"
FT /evidence="ECO:0000305|PubMed:18593701"
SQ SEQUENCE 267 AA; 30101 MW; 3FA373928A4C7FF8 CRC64;
MATKLISPPL SCPWVTSREV IIKGLPRRRR EWMVTKRNRV SAVTAMIVEP LSVVSSSAIQ
IHQWWEQNPN SLLLMTEATG GYSLASYYTS LGLFVISVPG LWSLIKRSVK SKIVRKTFVV
NDVKKEPKQV AGEILSFFTR KNFNITDRGE TITFEGKMVP SRGQAALLTF CTCISLASVG
LVLTITVPDF GNNWFFIILL SPLAGVYYWK KASRKEEIKV KMMVGSKGRL DEIVVQGDDV
QVEEMRKELQ LNEKGMVYVK GLFERSS
