ID   CCB21_ARATH             Reviewed;         429 AA.
AC   Q39068; Q9SHP1;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 2.
DT   25-MAY-2022, entry version 133.
DE   RecName: Full=Cyclin-B2-1;
DE   AltName: Full=Cyc2a-At;
DE   AltName: Full=Cyclin-2a;
DE   AltName: Full=G2/mitotic-specific cyclin-B2-1;
DE            Short=CycB2;1;
GN   Name=CYCB2-1; Synonyms=CYC2A; OrderedLocusNames=At2g17620;
GN   ORFNames=T19E12.4;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Columbia; TISSUE=Callus;
RX   PubMed=7972055; DOI=10.1073/pnas.91.24.11313;
RA   Ferreira P., Hemerly A., de Almeida Engler J., Bergounioux C., Burssens S.,
RA   van Montagu M., Engler G., Inze D.;
RT   "Three discrete classes of Arabidopsis cyclins are expressed during
RT   different intervals of the cell cycle.";
RL   Proc. Natl. Acad. Sci. U.S.A. 91:11313-11317(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=15208425; DOI=10.1104/pp.104.040436;
RA   Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA   Ma H.;
RT   "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT   phylogenetic analysis of plant cyclin-like proteins.";
RL   Plant Physiol. 135:1084-1099(2004).
RN   [5]
RP   INTERACTION WITH CDC20-1 AND CDC20-2.
RX   PubMed=21687678; DOI=10.1371/journal.pone.0020618;
RA   Kevei Z., Baloban M., Da Ines O., Tiricz H., Kroll A., Regulski K.,
RA   Mergaert P., Kondorosi E.;
RT   "Conserved CDC20 cell cycle functions are carried out by two of the five
RT   isoforms in Arabidopsis thaliana.";
RL   PLoS ONE 6:E20618-E20618(2011).
CC   -!- SUBUNIT: Interacts with CDC20-1 and CDC20-2.
CC       {ECO:0000269|PubMed:21687678}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and
CC       siliques. {ECO:0000269|PubMed:7972055}.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; Z31400; CAA83275.1; -; mRNA.
DR   EMBL; AC007509; AAD32949.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06658.1; -; Genomic_DNA.
DR   PIR; D84554; D84554.
DR   RefSeq; NP_179353.1; NM_127316.4.
DR   AlphaFoldDB; Q39068; -.
DR   SMR; Q39068; -.
DR   BioGRID; 1626; 2.
DR   IntAct; Q39068; 1.
DR   STRING; 3702.AT2G17620.1; -.
DR   PaxDb; Q39068; -.
DR   PRIDE; Q39068; -.
DR   ProteomicsDB; 224464; -.
DR   EnsemblPlants; AT2G17620.1; AT2G17620.1; AT2G17620.
DR   GeneID; 816269; -.
DR   Gramene; AT2G17620.1; AT2G17620.1; AT2G17620.
DR   KEGG; ath:AT2G17620; -.
DR   Araport; AT2G17620; -.
DR   TAIR; locus:2057243; AT2G17620.
DR   eggNOG; KOG0653; Eukaryota.
DR   HOGENOM; CLU_020695_0_0_1; -.
DR   InParanoid; Q39068; -.
DR   OMA; ANDFGDC; -.
DR   OrthoDB; 993640at2759; -.
DR   PhylomeDB; Q39068; -.
DR   PRO; PR:Q39068; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q39068; baseline and differential.
DR   Genevisible; Q39068; AT.
DR   GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   1: Evidence at protein level;
KW   Cell cycle; Cell division; Cyclin; Reference proteome.
FT   CHAIN           1..429
FT                   /note="Cyclin-B2-1"
FT                   /id="PRO_0000287012"
FT   CONFLICT        60
FT                   /note="R -> K (in Ref. 1; CAA83275)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        221
FT                   /note="I -> M (in Ref. 1; CAA83275)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   429 AA;  49243 MW;  B6E2DCFC4ED65770 CRC64;
     MVNSCENKIF VKPTSTTILQ DETRSRKFGQ EMKREKRRVL RVINQNLAGA RVYPCVVNKR
     GSLLSNKQEE EEGCQKKKFD SLRPSVTRSG VEEETNKKLK PSVPSANDFG DCIFIDEEEA
     TLDLPMPMSL EKPYIEADPM EEVEMEDVTV EEPIVDIDVL DSKNSLAAVE YVQDLYAFYR
     TMERFSCVPV DYMMQQIDLN EKMRAILIDW LIEVHDKFDL INETLFLTVN LIDRFLSKQN
     VMRKKLQLVG LVALLLACKY EEVSVPVVED LVLISDKAYT RNDVLEMEKT MLSTLQFNIS
     LPTQYPFLKR FLKAAQADKK CEVLASFLIE LALVEYEMLR FPPSLLAATS VYTAQCTLDG
     SRKWNSTCEF HCHYSEDQLM ECSRKLVSLH QRAATGNLTG VYRKYSTSKF GYIAKCEAAH
     FLVSESHHS