CCB21_ORYSJ
ID CCB21_ORYSJ Reviewed; 420 AA.
AC Q7XSJ6; B9FBZ8; Q9SSZ5;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2004, sequence version 2.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Cyclin-B2-1;
DE AltName: Full=CycB2-Os1;
DE AltName: Full=G2/mitotic-specific cyclin-B2-1;
DE Short=CycB2;1;
GN Name=CYCB2-1; Synonyms=CYCB2;
GN OrderedLocusNames=Os04g0563700, LOC_Os04g47580;
GN ORFNames=OsJ_15792 {ECO:0000312|EMBL:EEE61503.1}, OSJNBb0078D11.10;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, AND DEVELOPMENTAL
RP STAGE.
RC STRAIN=cv. Yamahoushi;
RX PubMed=10517318; DOI=10.1007/s004380051079;
RA Umeda M., Iwamoto N., Umeda-Hara C., Yamaguchi M., Hashimoto J.,
RA Uchimiya H.;
RT "Molecular characterization of mitotic cyclins in rice plants.";
RL Mol. Gen. Genet. 262:230-238(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND INDUCTION.
RX PubMed=9076986; DOI=10.1046/j.1365-313x.1997.11020181.x;
RA Sauter M.;
RT "Differential expression of a CAK (cdc2-activating kinase)-like protein
RT kinase, cyclins and cdc2 genes from rice during the cell cycle and in
RT response to gibberellin.";
RL Plant J. 11:181-190(1997).
RN [8]
RP DEVELOPMENTAL STAGE, AND INDUCTION.
RX PubMed=10987556; DOI=10.1007/s004250000295;
RA Fabian T., Lorbiecke R., Umeda M., Sauter M.;
RT "The cell cycle genes cycA1;1 and cdc2Os-3 are coordinately regulated by
RT gibberellin in planta.";
RL Planta 211:376-383(2000).
RN [9]
RP FUNCTION, DEVELOPMENTAL STAGE, AND INTERACTION WITH CDKB2-1.
RX PubMed=12753582; DOI=10.1046/j.1365-313x.2003.01736.x;
RA Lee J., Das A., Yamaguchi M., Hashimoto J., Tsutsumi N., Uchimiya H.,
RA Umeda M.;
RT "Cell cycle function of a rice B2-type cyclin interacting with a B-type
RT cyclin-dependent kinase.";
RL Plant J. 34:417-425(2003).
RN [10]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16435118; DOI=10.1007/s00438-005-0093-5;
RA La H., Li J., Ji Z., Cheng Y., Li X., Jiang S., Venkatesh P.N.,
RA Ramachandran S.;
RT "Genome-wide analysis of cyclin family in rice (Oryza sativa L.).";
RL Mol. Genet. Genomics 275:374-386(2006).
CC -!- FUNCTION: Involved in the control of the cell cycle at the G2/M
CC (mitosis) transition. May activate CDKB2-1 kinase.
CC {ECO:0000269|PubMed:10517318, ECO:0000269|PubMed:12753582}.
CC -!- SUBUNIT: Interacts with CDKB2-1. {ECO:0000269|PubMed:12753582}.
CC -!- TISSUE SPECIFICITY: Expressed in the root apices.
CC {ECO:0000269|PubMed:10517318, ECO:0000269|PubMed:9076986}.
CC -!- DEVELOPMENTAL STAGE: Expressed in the G2/M phases and disappears at the
CC anaphase of mitosis. {ECO:0000269|PubMed:10517318,
CC ECO:0000269|PubMed:10987556, ECO:0000269|PubMed:12753582,
CC ECO:0000269|PubMed:9076986}.
CC -!- INDUCTION: By gibberellic acid (GA3). {ECO:0000269|PubMed:10987556,
CC ECO:0000269|PubMed:9076986}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000305}.
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DR EMBL; AB024987; BAA86629.1; -; mRNA.
DR EMBL; AL606694; CAE01925.2; -; Genomic_DNA.
DR EMBL; AP008210; BAF15478.1; -; Genomic_DNA.
DR EMBL; AP014960; BAS90502.1; -; Genomic_DNA.
DR EMBL; CM000141; EEE61503.1; -; Genomic_DNA.
DR RefSeq; XP_015634273.1; XM_015778787.1.
DR AlphaFoldDB; Q7XSJ6; -.
DR SMR; Q7XSJ6; -.
DR STRING; 4530.OS04T0563700-01; -.
DR PaxDb; Q7XSJ6; -.
DR PRIDE; Q7XSJ6; -.
DR EnsemblPlants; Os04t0563700-01; Os04t0563700-01; Os04g0563700.
DR GeneID; 4336670; -.
DR Gramene; Os04t0563700-01; Os04t0563700-01; Os04g0563700.
DR KEGG; osa:4336670; -.
DR eggNOG; KOG0653; Eukaryota.
DR HOGENOM; CLU_020695_0_0_1; -.
DR InParanoid; Q7XSJ6; -.
DR OMA; ANDFGDC; -.
DR OrthoDB; 993640at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000007752; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR Genevisible; Q7XSJ6; OS.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR CDD; cd00043; CYCLIN; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177; PTHR10177; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; SSF47954; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Cyclin; Mitosis; Reference proteome.
FT CHAIN 1..420
FT /note="Cyclin-B2-1"
FT /id="PRO_0000287386"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 40
FT /note="P -> S (in Ref. 1; BAA86629)"
FT /evidence="ECO:0000305"
FT CONFLICT 71
FT /note="T -> L (in Ref. 1; BAA86629)"
FT /evidence="ECO:0000305"
FT CONFLICT 330
FT /note="A -> S (in Ref. 1; BAA86629)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 420 AA; 47294 MW; 10E9B99715C34DDE CRC64;
MDRASENRRL AAVGKPVPGI GEMGNRRPLR DINNLVGAPP HPSAIAKKPM LEKSGKEEQK
PALVVSHRPM TRNFAASLTR KEQLDHQVSV ADAAVVCTDP QKNPIPDGTV DDDVESCESN
DYIAVDECND TDEDESMMDI DSADSGNPLA ATEYVEELYK FYRENEEMSC VQPDYMSSQG
DINEKMRAIL IDWLIEVHHK FELMDETLFL TVNIVDRFLE KQVVPRKKLQ LVGVTAMLLA
CKYEEVAVPV VEDLVLISDR AYTKGQILEM EKLILNTLQF NMSVPTPYVF MRRFLKAAQS
DKQLQLLSFF ILELSLVEYQ MLKYRPSLLA AAAVYTAQCA LTRCQQWTKT CELHSRYTGE
QLLECSRMMV DFHQKAGAGK LTGVHRKYST FKFGCAAKTE PALFLLESGA GGYNLQKQPC
