CCB22_ORYSI
ID CCB22_ORYSI Reviewed; 419 AA.
AC A2YH60; Q40671; Q5Z7P8;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 2.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Cyclin-B2-2;
DE AltName: Full=CycOs2;
DE AltName: Full=G2/mitotic-specific cyclin-B2-2;
DE Short=CycB2;2;
GN Name=CYCB2-2; Synonyms=CYCOS2; ORFNames=OsI_023653;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND INDUCTION.
RC STRAIN=cv. Pin Gaew 53; TISSUE=Internode;
RX PubMed=7742859; DOI=10.1046/j.1365-313x.1995.7040623.x;
RA Sauter M., Mekhedov S.L., Kende H.;
RT "Gibberellin promotes histone H1 kinase activity and the expression of cdc2
RT and cyclin genes during the induction of rapid growth in deepwater rice
RT internodes.";
RL Plant J. 7:623-632(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Pin Gaew 53;
RA Sauter M.;
RT "Isolation and characterization of a cDNA encoding a mitotic cyclin of the
RT CycB2 type from rice.";
RL (er) Plant Gene Register PGR97-001(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [4]
RP DEVELOPMENTAL STAGE.
RX PubMed=9076986; DOI=10.1046/j.1365-313x.1997.11020181.x;
RA Sauter M.;
RT "Differential expression of a CAK (cdc2-activating kinase)-like protein
RT kinase, cyclins and cdc2 genes from rice during the cell cycle and in
RT response to gibberellin.";
RL Plant J. 11:181-190(1997).
RN [5]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=10517318; DOI=10.1007/s004380051079;
RA Umeda M., Iwamoto N., Umeda-Hara C., Yamaguchi M., Hashimoto J.,
RA Uchimiya H.;
RT "Molecular characterization of mitotic cyclins in rice plants.";
RL Mol. Gen. Genet. 262:230-238(1999).
RN [6]
RP TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND INDUCTION.
RX PubMed=9880342; DOI=10.1104/pp.119.1.21;
RA Lorbiecke R., Sauter M.;
RT "Adventitious root growth and cell-cycle induction in deepwater rice.";
RL Plant Physiol. 119:21-30(1999).
RN [7]
RP FUNCTION, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, AND INTERACTION WITH
RP CDKB2-1.
RX PubMed=12753582; DOI=10.1046/j.1365-313x.2003.01736.x;
RA Lee J., Das A., Yamaguchi M., Hashimoto J., Tsutsumi N., Uchimiya H.,
RA Umeda M.;
RT "Cell cycle function of a rice B2-type cyclin interacting with a B-type
RT cyclin-dependent kinase.";
RL Plant J. 34:417-425(2003).
CC -!- FUNCTION: Involved in the control of the cell cycle at the G2/M
CC (mitosis) transition. May associate to CDKB2-1 and activate CDKB2-1
CC kinase to promote cell division. {ECO:0000269|PubMed:10517318,
CC ECO:0000269|PubMed:12753582}.
CC -!- SUBUNIT: Interacts with CDKB2-1. {ECO:0000269|PubMed:12753582}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12753582}.
CC Note=Expressed during interphase, prophase, metaphase and disappears at
CC anaphase and telophase.
CC -!- TISSUE SPECIFICITY: Expressed in the intercalary meristem and the
CC elongation zone of internodes. Expressed in adventitious roots at all
CC nodes under submergence conditions. {ECO:0000269|PubMed:10517318,
CC ECO:0000269|PubMed:7742859, ECO:0000269|PubMed:9880342}.
CC -!- DEVELOPMENTAL STAGE: Expressed in the G2/M phases and disappears at the
CC anaphase of mitosis. {ECO:0000269|PubMed:12753582,
CC ECO:0000269|PubMed:9076986, ECO:0000269|PubMed:9880342}.
CC -!- INDUCTION: By gibberellic acid (GA3) and submergence.
CC {ECO:0000269|PubMed:7742859, ECO:0000269|PubMed:9880342}.
CC -!- MISCELLANEOUS: May be involved in rapid internodal growth of indica
CC deepwater rice under submergence.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X82036; CAA57556.1; -; mRNA.
DR EMBL; CM000131; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; T03675; T03675.
DR AlphaFoldDB; A2YH60; -.
DR SMR; A2YH60; -.
DR STRING; 39946.A2YH60; -.
DR Proteomes; UP000007015; Chromosome 6.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd00043; CYCLIN; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177; PTHR10177; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; SSF47954; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Cyclin; Mitosis; Nucleus; Reference proteome.
FT CHAIN 1..419
FT /note="Cyclin-B2-2"
FT /id="PRO_0000292942"
FT REGION 79..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 63
FT /note="A -> S (in Ref. 1; CAA57556)"
FT /evidence="ECO:0000305"
FT CONFLICT 82
FT /note="S -> I (in Ref. 1; CAA57556)"
FT /evidence="ECO:0000305"
FT CONFLICT 404
FT /note="A -> P (in Ref. 1; CAA57556)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 419 AA; 47504 MW; D9C1FBC55D658346 CRC64;
MENMRSENFN QGVSMEGVKH APEMANTNRR ALRDIKNIIG APHQHMAVSK RGLLDKPAAK
NQAGHRPMTR KFAATLANQP SSAPLAPIGS ERQKRTADSA FHGPADMECT KITSDDLPLP
MMSEMDEVMG SELKEIEMED IEEAAPDIDS CDANNSLAVV EYVDEIYSFY RRSEGLSCVS
PNYMLSQNDI NEKMRGILID WLIEVHYKLE LLDETLFLTV NIIDRFLARE NVVRKKLQLV
GVTAMLLACK YEEVSVPVVE DLILICDRAY TRTDILEMER MIVNTLQFDM SVPTPYCFMR
RFLKAAQSDK KLELMSFFII ELSLVEYEML KFQPSMLAAA AIYTAQCTIN GFKSWNKCCE
LHTKYSEEQL MECSKMMVEL HQKAGHGKLT GVHRKYSTFR YGCAAKSEPA VFLLKSVAL
