ID   CCB22_ORYSJ             Reviewed;         419 AA.
AC   Q0D9C7; B7EI05; Q40671; Q5Z7P8;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Cyclin-B2-2;
DE   AltName: Full=CycB2-Os2;
DE   AltName: Full=G2/mitotic-specific cyclin-B2-2;
DE            Short=CycB2;2;
GN   Name=CYCB2-2; Synonyms=CYCB2;
GN   OrderedLocusNames=Os06g0726800, LOC_Os06g51110; ORFNames=P0017G10.10;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [5]
RP   FUNCTION, AND TISSUE SPECIFICITY.
RX   PubMed=10517318; DOI=10.1007/s004380051079;
RA   Umeda M., Iwamoto N., Umeda-Hara C., Yamaguchi M., Hashimoto J.,
RA   Uchimiya H.;
RT   "Molecular characterization of mitotic cyclins in rice plants.";
RL   Mol. Gen. Genet. 262:230-238(1999).
RN   [6]
RP   FUNCTION, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, AND INTERACTION WITH
RP   CDKB2-1.
RX   PubMed=12753582; DOI=10.1046/j.1365-313x.2003.01736.x;
RA   Lee J., Das A., Yamaguchi M., Hashimoto J., Tsutsumi N., Uchimiya H.,
RA   Umeda M.;
RT   "Cell cycle function of a rice B2-type cyclin interacting with a B-type
RT   cyclin-dependent kinase.";
RL   Plant J. 34:417-425(2003).
RN   [7]
RP   INTERACTION WITH MRS2-F AND MRS2-G.
RX   PubMed=14750518; DOI=10.1023/b:plan.0000007001.30865.0f;
RA   Cooper B., Hutchison D., Park S., Guimil S., Luginbuehl P., Ellero C.,
RA   Goff S.A., Glazebrook J.;
RT   "Identification of rice (Oryza sativa) proteins linked to the cyclin-
RT   mediated regulation of the cell cycle.";
RL   Plant Mol. Biol. 53:273-279(2003).
RN   [8]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16435118; DOI=10.1007/s00438-005-0093-5;
RA   La H., Li J., Ji Z., Cheng Y., Li X., Jiang S., Venkatesh P.N.,
RA   Ramachandran S.;
RT   "Genome-wide analysis of cyclin family in rice (Oryza sativa L.).";
RL   Mol. Genet. Genomics 275:374-386(2006).
CC   -!- FUNCTION: Involved in the control of the cell cycle at the G2/M
CC       (mitosis) transition. May associate to CDKB2-1 and activate CDKB2-1
CC       kinase activity to promote cell division. {ECO:0000269|PubMed:10517318,
CC       ECO:0000269|PubMed:12753582}.
CC   -!- SUBUNIT: Interacts with CDKB2-1, MRS2-F and MRS2-G.
CC       {ECO:0000269|PubMed:12753582, ECO:0000269|PubMed:14750518}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12753582}.
CC       Note=Expressed during interphase, prophase, metaphase and disappears at
CC       anaphase and telophase.
CC   -!- TISSUE SPECIFICITY: Expressed in the root apices.
CC       {ECO:0000269|PubMed:10517318}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in the G2/M phases and disappears at the
CC       anaphase of mitosis. {ECO:0000269|PubMed:12753582}.
CC   -!- INDUCTION: By gibberellic acid (GA3).
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AP004685; BAD61808.1; -; Genomic_DNA.
DR   EMBL; AP008212; BAF20546.1; -; Genomic_DNA.
DR   EMBL; AP014962; BAS99605.1; -; Genomic_DNA.
DR   EMBL; AK070518; BAG92002.1; -; mRNA.
DR   RefSeq; XP_015641959.1; XM_015786473.1.
DR   RefSeq; XP_015641961.1; XM_015786475.1.
DR   AlphaFoldDB; Q0D9C7; -.
DR   SMR; Q0D9C7; -.
DR   STRING; 4530.OS06T0726800-01; -.
DR   PaxDb; Q0D9C7; -.
DR   PRIDE; Q0D9C7; -.
DR   EnsemblPlants; Os06t0726800-01; Os06t0726800-01; Os06g0726800.
DR   GeneID; 4342121; -.
DR   Gramene; Os06t0726800-01; Os06t0726800-01; Os06g0726800.
DR   KEGG; osa:4342121; -.
DR   eggNOG; KOG0653; Eukaryota.
DR   HOGENOM; CLU_020695_0_0_1; -.
DR   InParanoid; Q0D9C7; -.
DR   OMA; PMLSEMD; -.
DR   OrthoDB; 993640at2759; -.
DR   Proteomes; UP000000763; Chromosome 6.
DR   Proteomes; UP000059680; Chromosome 6.
DR   Genevisible; Q0D9C7; OS.
DR   GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   1: Evidence at protein level;
KW   Cell cycle; Cell division; Cyclin; Mitosis; Nucleus; Reference proteome.
FT   CHAIN           1..419
FT                   /note="Cyclin-B2-2"
FT                   /id="PRO_0000080396"
FT   REGION          79..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   419 AA;  47504 MW;  D9C1FBC55D658346 CRC64;
     MENMRSENFN QGVSMEGVKH APEMANTNRR ALRDIKNIIG APHQHMAVSK RGLLDKPAAK
     NQAGHRPMTR KFAATLANQP SSAPLAPIGS ERQKRTADSA FHGPADMECT KITSDDLPLP
     MMSEMDEVMG SELKEIEMED IEEAAPDIDS CDANNSLAVV EYVDEIYSFY RRSEGLSCVS
     PNYMLSQNDI NEKMRGILID WLIEVHYKLE LLDETLFLTV NIIDRFLARE NVVRKKLQLV
     GVTAMLLACK YEEVSVPVVE DLILICDRAY TRTDILEMER MIVNTLQFDM SVPTPYCFMR
     RFLKAAQSDK KLELMSFFII ELSLVEYEML KFQPSMLAAA AIYTAQCTIN GFKSWNKCCE
     LHTKYSEEQL MECSKMMVEL HQKAGHGKLT GVHRKYSTFR YGCAAKSEPA VFLLKSVAL