ID   CCB23_HOMAM             Reviewed;         137 AA.
AC   P80364;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Crustacean calcium-binding protein 23;
DE            Short=CCBP-23;
DE   Flags: Fragments;
OS   Homarus americanus (American lobster).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;
OC   Nephropoidea; Nephropidae; Homarus.
OX   NCBI_TaxID=6706;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Muscle;
RX   PubMed=7851448; DOI=10.1111/j.1432-1033.1995.tb20363.x;
RA   Sauter A., Staudenmann W., Hughes G.J., Heizmann C.W.;
RT   "A novel EF-hand Ca(2+)-binding protein from abdominal muscle of
RT   crustaceans with similarity to calcyphosine from dog thyroidea.";
RL   Eur. J. Biochem. 227:97-101(1995).
CC   -!- FUNCTION: Possibly acts as a regulatory protein and not as a calcium
CC       buffer or transport protein.
CC   -!- SUBUNIT: Monomer or disulfide-linked dimers.
CC   -!- MISCELLANEOUS: This protein binds calcium.
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DR   AlphaFoldDB; P80364; -.
DR   SMR; P80364; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   1: Evidence at protein level;
KW   Calcium; Direct protein sequencing; Disulfide bond; Metal-binding; Repeat.
FT   CHAIN           <1..>137
FT                   /note="Crustacean calcium-binding protein 23"
FT                   /id="PRO_0000073543"
FT   DOMAIN          27..48
FT                   /note="EF-hand 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          62..97
FT                   /note="EF-hand 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          100..135
FT                   /note="EF-hand 3"
FT                   /evidence="ECO:0000305"
FT   UNSURE          5
FT                   /note="L or I"
FT   UNSURE          12
FT                   /note="L or I"
FT   UNSURE          16
FT                   /note="L or I"
FT   UNSURE          19
FT                   /note="L or I"
FT   UNSURE          20
FT                   /note="L or I"
FT   UNSURE          22
FT                   /note="L or I"
FT   UNSURE          25
FT                   /note="L or I"
FT   UNSURE          33
FT                   /note="L or I"
FT   UNSURE          38
FT                   /note="L or I"
FT   UNSURE          47
FT                   /note="L or I"
FT   UNSURE          57
FT                   /note="L or I"
FT   UNSURE          74
FT                   /note="L or I"
FT   UNSURE          87
FT                   /note="I or L"
FT   UNSURE          105
FT                   /note="I or L"
FT   UNSURE          106
FT                   /note="L or I"
FT   UNSURE          110
FT                   /note="L or I"
FT   UNSURE          129
FT                   /note="L or I"
FT   UNSURE          135
FT                   /note="L or I"
FT   NON_CONS        8..9
FT                   /evidence="ECO:0000305"
FT   NON_CONS        27..28
FT                   /evidence="ECO:0000305"
FT   NON_CONS        63..64
FT                   /evidence="ECO:0000305"
FT   NON_CONS        94..95
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
FT   NON_TER         137
SQ   SEQUENCE   137 AA;  15055 MW;  DB7F779A5074ED72 CRC64;
     DTAPLEKKSH CLSQGLSGLL SLGKLFRDSS WTLSKEELSR GVSQFGLDFS DADVNKLFSD
     FEKKAAVEAA FKHLDKTGDG VVTVEDIKGV YSAKVVKGEA TEEEILKKFL NMFESSTSVD
     GKVTKKEFLD YYSGLSK