ID   CCCP_DROYA              Reviewed;         260 AA.
AC   Q24764;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Circadian clock-controlled protein daywake {ECO:0000250|UniProtKB:O76879};
DE   Flags: Precursor;
GN   Name=dyw {ECO:0000250|UniProtKB:O76879};
GN   Synonyms=anon-3B1.2 {ECO:0000250|UniProtKB:O76879}; ORFNames=GE16930;
OS   Drosophila yakuba (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7245;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1702156; DOI=10.1007/bf02106054;
RA   Thackeray J.R., Kyriacou C.P.;
RT   "Molecular evolution in the Drosophila yakuba period locus.";
RL   J. Mol. Evol. 31:389-401(1990).
CC   -!- FUNCTION: Component of the circadian clock or downstream effector of
CC       clock function. Required for suppressing daytime sleep (siesta) under
CC       ambient environmental temperatures. Part of a heat avoidance mechanism
CC       that modulates daytime sleep behavior under different environmental
CC       temperatures to minimize the risk of heat exposure. Under cooler
CC       ambient temperatures, suppresses daytime sleep (siesta) and thus allows
CC       for longer periods of daytime activity. {ECO:0000250|UniProtKB:O76879}.
CC   -!- SIMILARITY: Belongs to the TO family. {ECO:0000305}.
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DR   EMBL; X84413; CAA59131.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q24764; -.
DR   SMR; Q24764; -.
DR   STRING; 7245.FBpp0261940; -.
DR   eggNOG; ENOG502T6I4; Eukaryota.
DR   GO; GO:0007623; P:circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0010841; P:positive regulation of circadian sleep/wake cycle, wakefulness; IEA:EnsemblMetazoa.
DR   Gene3D; 3.15.10.30; -; 1.
DR   InterPro; IPR010562; Haemolymph_juvenile_hormone-bd.
DR   InterPro; IPR038606; To_sf.
DR   Pfam; PF06585; JHBP; 1.
DR   SMART; SM00700; JHBP; 1.
PE   3: Inferred from homology;
KW   Biological rhythms; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..260
FT                   /note="Circadian clock-controlled protein daywake"
FT                   /id="PRO_0000020861"
SQ   SEQUENCE   260 AA;  29365 MW;  BCB5A66E55AF7126 CRC64;
     MQLTSASVCL LWMGLLSWVS HRIDASQGFP SPLKRCKLQE ESCLVAQAQT FFQAFQKGIP
     ERQVAALEPI DLGTMRIESG GHSESLKFKL VMSDAKLYNL ANSVVVKSLK GFTKDLTKPL
     KLTLLMDTPE LEVRAKYDVD GKLLILPIVS KGDLTIRMNE VQTKRRITAE PVKRSDGHSY
     LNITDYKTIT KIKGGHFDLS NLFDDNKELR ESTLKVLNQE WNTLALDVQP KINEACSKAF
     RAILQSLWAN IPYDEFFKAE