CCD11_ARATH
ID CCD11_ARATH Reviewed; 339 AA.
AC P42751; O04525; Q8W2K2;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 3.
DT 03-AUG-2022, entry version 145.
DE RecName: Full=Cyclin-D1-1;
DE AltName: Full=Cyclin-delta-1;
DE Short=Cyclin-d1;
DE AltName: Full=G1/S-specific cyclin-D1-1;
DE Short=CycD1;1;
GN Name=CYCD1-1; Synonyms=CYCD1; OrderedLocusNames=At1g70210;
GN ORFNames=F20P5.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Landsberg erecta; TISSUE=Seedling;
RX PubMed=7696881; DOI=10.2307/3869840;
RA Soni R., Carmichael J.P., Shah Z.H., Murray J.A.H.;
RT "A family of cyclin D homologs from plants differentially controlled by
RT growth regulators and containing the conserved retinoblastoma protein
RT interaction motif.";
RL Plant Cell 7:85-103(1995).
RN [2]
RP SEQUENCE REVISION.
RA Murray J.A.H.;
RL Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [7]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-120, AND INTERACTION WITH KRP6/ICK4.
RX PubMed=15464981; DOI=10.1016/j.bbrc.2004.08.233;
RA Cho J.W., Park S.C., Shin E.A., Kim C.K., Han W., Sohn S.-I., Song P.S.,
RA Wang M.-H.;
RT "Cyclin D1 and p22ack1 play opposite roles in plant growth and
RT development.";
RL Biochem. Biophys. Res. Commun. 324:52-57(2004).
RN [8]
RP INTERACTION WITH CDKA-1.
RX PubMed=10100639; DOI=10.1016/s0014-5793(99)00211-2;
RA Porceddu A., de Veylder L., Hayles J., van Montagu M., Inze D., Mironov V.;
RT "Mutational analysis of two Arabidopsis thaliana cyclin-dependent kinases
RT in fission yeast.";
RL FEBS Lett. 446:182-188(1999).
RN [9]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15208425; DOI=10.1104/pp.104.040436;
RA Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA Ma H.;
RT "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT phylogenetic analysis of plant cyclin-like proteins.";
RL Plant Physiol. 135:1084-1099(2004).
RN [10]
RP FUNCTION, AND DEVELOPMENTAL STAGE.
RX PubMed=16227434; DOI=10.1073/pnas.0507581102;
RA Masubelele N.H., Dewitte W., Menges M., Maughan S., Collins C., Huntley R.,
RA Nieuwland J., Scofield S., Murray J.A.H.;
RT "D-type cyclins activate division in the root apex to promote seed
RT germination in Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:15694-15699(2005).
CC -!- FUNCTION: May activate cell cycle in the root apical meristem (RAM) and
CC promote embryonic root (radicle) protrusion.
CC {ECO:0000269|PubMed:16227434}.
CC -!- SUBUNIT: Interacts with CDKA-1 and KRP6/ICK4.
CC {ECO:0000269|PubMed:10100639, ECO:0000269|PubMed:15464981}.
CC -!- INTERACTION:
CC P42751; Q8LF80: CDKB2-1; NbExp=2; IntAct=EBI-2025690, EBI-1253579;
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves and flowers.
CC {ECO:0000269|PubMed:7696881}.
CC -!- DEVELOPMENTAL STAGE: Transiently expressed in the root tip during seed
CC germination up to about 21 hours after stratification.
CC {ECO:0000269|PubMed:16227434}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin D subfamily.
CC {ECO:0000305}.
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DR EMBL; X83369; CAA58285.1; -; mRNA.
DR EMBL; AC002062; AAB61096.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35034.1; -; Genomic_DNA.
DR EMBL; AK117189; BAC41865.1; -; mRNA.
DR EMBL; BT005315; AAO63379.1; -; mRNA.
DR EMBL; AF208693; AAL35986.1; -; Genomic_DNA.
DR PIR; A96725; A96725.
DR PIR; S51650; S51650.
DR RefSeq; NP_177178.1; NM_105689.4.
DR AlphaFoldDB; P42751; -.
DR SMR; P42751; -.
DR BioGRID; 28578; 13.
DR IntAct; P42751; 4.
DR STRING; 3702.AT1G70210.1; -.
DR PaxDb; P42751; -.
DR PRIDE; P42751; -.
DR DNASU; 843357; -.
DR EnsemblPlants; AT1G70210.1; AT1G70210.1; AT1G70210.
DR GeneID; 843357; -.
DR Gramene; AT1G70210.1; AT1G70210.1; AT1G70210.
DR KEGG; ath:AT1G70210; -.
DR Araport; AT1G70210; -.
DR TAIR; locus:2020663; AT1G70210.
DR eggNOG; KOG0656; Eukaryota.
DR HOGENOM; CLU_048040_2_0_1; -.
DR InParanoid; P42751; -.
DR OMA; GFFISHA; -.
DR OrthoDB; 1234739at2759; -.
DR PhylomeDB; P42751; -.
DR PRO; PR:P42751; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; P42751; baseline and differential.
DR Genevisible; P42751; AT.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR CDD; cd00043; CYCLIN; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR InterPro; IPR036280; Multihaem_cyt_sf.
DR PANTHER; PTHR10177; PTHR10177; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 1.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; SSF47954; 1.
DR SUPFAM; SSF48695; SSF48695; 1.
DR PROSITE; PS00292; CYCLINS; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Cyclin; Reference proteome.
FT CHAIN 1..339
FT /note="Cyclin-D1-1"
FT /id="PRO_0000080445"
FT CONFLICT 314..317
FT /note="Missing (in Ref. 1; CAA58285)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 339 AA; 38277 MW; 65D2449D5DBCE9D6 CRC64;
MRSYRFSDYL HMSVSFSNDM DLFCGEDSGV FSGESTVDFS SSEVDSWPGD SIACFIEDER
HFVPGHDYLS RFQTRSLDAS AREDSVAWIL KVQAYYNFQP LTAYLAVNYM DRFLYARRLP
ETSGWPMQLL AVACLSLAAK MEEILVPSLF DFQVAGVKYL FEAKTIKRME LLVLSVLDWR
LRSVTPFDFI SFFAYKIDPS GTFLGFFISH ATEIILSNIK EASFLEYWPS SIAAAAILCV
ANELPSLSSV VNPHESPETW CDGLSKEKIV RCYRLMKAMA IENNRLNTPK VIAKLRVSVR
ASSTLTRPSD ESSFSSSSPC KRRKLSGYSW VGDETSTSN
