ID   CCD12_ORYSJ             Reviewed;         354 AA.
AC   Q8H339;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 2.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Cyclin-D1-2;
DE   AltName: Full=G1/S-specific cyclin-D1-2;
DE            Short=CycD1;2;
GN   Name=CYCD1-2; OrderedLocusNames=Os08g0421100, LOC_Os08g32540;
GN   ORFNames=OJ1188_F05.24, OSJNBa0077M12.105;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16435118; DOI=10.1007/s00438-005-0093-5;
RA   La H., Li J., Ji Z., Cheng Y., Li X., Jiang S., Venkatesh P.N.,
RA   Ramachandran S.;
RT   "Genome-wide analysis of cyclin family in rice (Oryza sativa L.).";
RL   Mol. Genet. Genomics 275:374-386(2006).
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin D subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC24951.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAC99455.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP004005; BAC99455.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP005301; BAC24951.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015648967.1; XM_015793481.1.
DR   RefSeq; XP_015648968.1; XM_015793482.1.
DR   AlphaFoldDB; Q8H339; -.
DR   SMR; Q8H339; -.
DR   STRING; 4530.OS08T0421100-00; -.
DR   PaxDb; Q8H339; -.
DR   PRIDE; Q8H339; -.
DR   GeneID; 9272445; -.
DR   KEGG; osa:9272445; -.
DR   eggNOG; KOG0656; Eukaryota.
DR   InParanoid; Q8H339; -.
DR   OrthoDB; 993640at2759; -.
DR   Proteomes; UP000000763; Chromosome 8.
DR   Proteomes; UP000059680; Chromosome 8.
DR   GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR   CDD; cd00043; CYCLIN; 1.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   SMART; SM00385; CYCLIN; 1.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cyclin; Reference proteome.
FT   CHAIN           1..354
FT                   /note="Cyclin-D1-2"
FT                   /id="PRO_0000287021"
FT   REGION          37..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          331..354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        331..345
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   354 AA;  38567 MW;  9310E236E67CEBDD CRC64;
     MGAPATAASG GGDDDDRDVV FEYLLCTEED AASAGSFFQQ LQGPAPAVSS SPSTTTATAP
     AAAGSCDDGG EEEEEEVWTV DVVAELIGGE AERSHSPRAD YPGRLRSGRP ADLAARADSV
     AWILKVRELY GMLPVTAYLA VSYMDRFLSL HRLPGNGWAM QLLAVTCLSL AAKMEETLVP
     SILDLQMEDA RYIFEHRTIF RMELLVLDAL DWRLRSITPF TFMYLFADKV DPNGKHIREL
     IHQATQVTLA TIHDTEFLDH CPSSIAAAAV LCASSEIMQL VSIDHGTLVS WRIIGLDEEA
     IIRCYRLMQQ LISSNNVGRE STEITMATTT TTATTAVSSE EVVSSSPPSK RRKM