CCD17_MOUSE
ID CCD17_MOUSE Reviewed; 565 AA.
AC Q8CE13; B0QZT6; Q8BTE7;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Coiled-coil domain-containing protein 17;
GN Name=Ccdc17;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Embryo, and Head;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
CC -!- SEQUENCE CAUTION:
CC Sequence=CAQ11117.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AK003161; BAC25021.1; -; mRNA.
DR EMBL; AK029257; BAC26359.1; -; mRNA.
DR EMBL; AL669953; CAQ11117.1; ALT_SEQ; Genomic_DNA.
DR CCDS; CCDS18512.1; -.
DR RefSeq; NP_001033005.1; NM_001037916.3.
DR AlphaFoldDB; Q8CE13; -.
DR SMR; Q8CE13; -.
DR STRING; 10090.ENSMUSP00000059848; -.
DR iPTMnet; Q8CE13; -.
DR PhosphoSitePlus; Q8CE13; -.
DR MaxQB; Q8CE13; -.
DR PaxDb; Q8CE13; -.
DR PRIDE; Q8CE13; -.
DR ProteomicsDB; 265704; -.
DR Antibodypedia; 51288; 116 antibodies from 18 providers.
DR Ensembl; ENSMUST00000051869; ENSMUSP00000059848; ENSMUSG00000034035.
DR GeneID; 622665; -.
DR KEGG; mmu:622665; -.
DR UCSC; uc008ugu.1; mouse.
DR CTD; 149483; -.
DR MGI; MGI:1915667; Ccdc17.
DR VEuPathDB; HostDB:ENSMUSG00000034035; -.
DR eggNOG; ENOG502QR6M; Eukaryota.
DR GeneTree; ENSGT00390000006459; -.
DR HOGENOM; CLU_040615_0_0_1; -.
DR InParanoid; Q8CE13; -.
DR OMA; RFCIGHL; -.
DR OrthoDB; 789769at2759; -.
DR PhylomeDB; Q8CE13; -.
DR TreeFam; TF335390; -.
DR BioGRID-ORCS; 622665; 5 hits in 71 CRISPR screens.
DR ChiTaRS; Ccdc17; mouse.
DR PRO; PR:Q8CE13; -.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; Q8CE13; protein.
DR Bgee; ENSMUSG00000034035; Expressed in right kidney and 73 other tissues.
DR InterPro; IPR038800; CCDC17.
DR PANTHER; PTHR33820; PTHR33820; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..565
FT /note="Coiled-coil domain-containing protein 17"
FT /id="PRO_0000302853"
FT REGION 58..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 97..160
FT /evidence="ECO:0000255"
FT COILED 219..271
FT /evidence="ECO:0000255"
FT COMPBIAS 58..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 565 AA; 62536 MW; 930324EE618637F1 CRC64;
MADYSGESGL LSCESCDMVF RSWALLATHT KRFCIGRLTP EVTLKSQPSV AIKRGTKIMA
QEKSRDQEAS TSALKRLTEE TAGSPGERLR VLQGTRARRM AETEAQSRAL ERRGEELKRR
LHSVAGPKGG LPRPFDLERE LRELKEEANR TRGALQTLGA HFQALQLQPR KLQDTHRAVE
FCYLPLRFNP ETLAAEIRIL REAYVHGGGR DPEVLDKILQ LQVEASALEL QRSQNRKEKL
SAASEEVLTV EAENRLLEAE ILALQKQKVL SLSPWGSRDL PGHLSRCDNS LLPPLVAPPI
PQLTSSTKAQ NFHGTSKTIL NGTMTRKMGL DLHFLLPASD VLGPAPYDPG AGLVIFYDFL
RGLDTSWIWV QLMTSLARNG QDTGGTTALP PALCLPQPSA PGPMGNCAIL ASKQPVPRLP
PSPLVSLICE LQAWHGVTWA PQPKAWASLL LFDQDLRVLR GRWRLPLRVY PNTSLSLAQR
NEIPQAGQAE LFLRLVNARD TDAQTLAEIN PANAHEYQYP PMVSSSSVES SFFTHSSAFA
DPPPPTEEAF VSVKDKNEHL SPHQF